Abstract
In the course of its 30 years of development, chemotherapy has acquired a firm place in the treatment of human cancer in addition to the classical methods of surgery and radiation therapy, which have been of considerable benefit in fighting primary tumours. By their very nature, surgery and radiation therapy are local or regional measures. By the time of diagnosis more than two thirds of all malignant tumours have spread beyond their local borders so that therapeutic benefit can only be expected from additional systemic treatment and therefore chemotherapy has its preferential potentialities in such generalized tumour conditions. This conclusion invariably applies irrespective of whether the present drugs are satisfactory or not.
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Brock, N. (1976). Experimental Basis of Cancer Chemotherapy. In: Hellmann, K., Connors, T.A. (eds) Chemotherapy. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-4349-3_2
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DOI: https://doi.org/10.1007/978-1-4613-4349-3_2
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