Skip to main content
SpringerLink
Log in

The Regulation of Thyroid Cell Metabolism

  • Chapter
Book cover Eukaryotic Cell Function and Growth

Abstract

The metabolism of the thyroid is principally regulated by the pituitary hormone thyrotropin. Other signals also influence this metabolism (see article included in this volume by Marshall), e.g. adrenalin, noradrenalin, acetylcholine, serotonin, etc. (1, 2) but their physiological role is still largely unknown. The action of thyrotropin on the thyroid has been reviewed recently (3). However, since that review, much new information has been provided on the intracellular regulatory circuits in this tissue. In this chapter the role of the cyclic nucleotides cAMP and cGMP, calcium and iodide will be considered. Aspects of these regulations which are peculiar to the thyroid or which may bear on other tissues but have not been considered yet will be emphasized. The role of prostaglandins (Jacquemin, see this volume) and of postaglandin, adrenergic agents, and immunoglobulins (Marshall, see this volume) in the regulation of the thyroid is analyzed in other chapters. Most of the results presented have been obtained in this laboratory.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 39.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 54.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Söderberg, V., (1959), Physiol. Rev., 39, 777

    PubMed  Google Scholar 

  2. Melander, A., Erisson, L.E. and Sunder, F., (1974) Life Sci., 14, 237

    Article  PubMed  CAS  Google Scholar 

  3. Dumont, J.E. (1971), Vit. Hormones, 29, 287

    Article  CAS  Google Scholar 

  4. Vassart, G., Brocas, H., Lecocq, R. and Dumont, J,E., (1975) Europ. J. Biochem. 55, 15

    Article  PubMed  CAS  Google Scholar 

  5. Taurog, A., (1970), Rec. Progr. Horn. Res., 26, 189

    CAS  Google Scholar 

  6. Pommier, J., De Prailaume, S., and Nunez, J. (1972), Biochimie, 54, 483

    Article  PubMed  CAS  Google Scholar 

  7. Pantic, V.R., (1974), Int. Rev. Cytol., 38, 153

    Article  PubMed  CAS  Google Scholar 

  8. Neve, P., Willems, C., and Dumont, J.E. (1970), Exptl. Cell Res., 63, 457

    Article  PubMed  CAS  Google Scholar 

  9. Wolff, J., and Williams, J.A., (1973), Rec. Progr. Horn. Res., 29, 229

    CAS  Google Scholar 

  10. Dumont, J.E., and Tondeur-Montenez, T. (1965), Biochim. Biophys. Acta, 3, 258

    Google Scholar 

  11. Bates, R.W. and Condliffe, P.G. (1960), Rec. Progr. Horn. Res., 16, 309

    CAS  Google Scholar 

  12. Dumont, J.E., and Rocmans, P., (1964), J. Physiol. 174, 26

    PubMed  CAS  Google Scholar 

  13. Dumont, J.E., Willems, C., Van Sande, J. and Neve, P., (1971) Ann. N.Y. Acad. Sci., 185, 291

    Article  PubMed  CAS  Google Scholar 

  14. Tong, W. (1964), Endocrinology, 75, 527

    Article  PubMed  CAS  Google Scholar 

  15. Kerkof, P.R.,Long, P.J. and Chaikoff, I.L., (1964) Endocrinology, 74, 170

    Article  PubMed  CAS  Google Scholar 

  16. Neve, P., Rodesch, F and Dumont, J.E., (1968), Exptl. Cell Res., 51, 68

    Article  PubMed  CAS  Google Scholar 

  17. Fayet, G., Pacheco, H., and Tixier, R., (1970), Bull. Soc. Chim. Biol., 52, 299

    PubMed  CAS  Google Scholar 

  18. Van Sande, J. and Dumont, J.E., (1973) Biochim. Biophys. Acta, 313, 320

    PubMed  Google Scholar 

  19. Gilman, A.G. (1970), Proceed. Natl. Acad. Sci. ( US ), 67, 305

    Article  CAS  Google Scholar 

  20. Murad, F., Manganiello, V. and Vaughan, M. (1971), Proceed. Natl. Acad. Sci. ( Us ), 68, 736

    Article  CAS  Google Scholar 

  21. Van Sande, J., Decoster, C. and Dumont, J.E. (1975), Biochem. Biophys. Res. Comm., 62, 168

    Article  PubMed  Google Scholar 

  22. Lamy, F. and Dumont, J.E., (1974), Europ. J. Biochem., 45, 171

    Article  PubMed  CAS  Google Scholar 

  23. Rodesch, F., Neve, P., Willems, C. and Dumont, J.E. (1968), Europ. J. Biochem., 8, 26

    Article  Google Scholar 

  24. Sutherland, E.W., Øye, I and R.W. Butcher, (1965) Rec. Progr. Horn. Res., 21, 623

    CAS  Google Scholar 

  25. Pochet, R., Boeynaems, J.M. and Dumont, J.E., (1974) Biochem. Biophys. Res. Comm., 58, 446

    Article  PubMed  CAS  Google Scholar 

  26. Langan, T.A. (1969) Proceed. Natl. Acad. Sci. ( Us ), 64, 1276

    Article  CAS  Google Scholar 

  27. Lamy, F., Willems, C., Lecoco, R., Delcroix, C. and Dumont, J.E., (1971), Horm. Metab. Res., 3, 414

    Article  PubMed  CAS  Google Scholar 

  28. Boeynaems, J.M., Golsteon-Golaire, J. and Dumont, J.E., (1975) Endocrinology, 93, 1227

    Article  Google Scholar 

  29. Van Sande, J. and Dumont, J.E., (1975), Mol. Cell. Endocr. 2, 289

    Article  Google Scholar 

  30. Boeynaems, J.M., Van Sande, J., Pochet, R. and Dumont, J.E. (1974) Mol. Cell. Endocr., 1, 135

    Article  Google Scholar 

  31. Van Sande, J., Grenier, G., Willems, C. and Dumont, J.E. (1975), 96, 781

    Google Scholar 

  32. Shimizu, T. and Shishiba, Y., (1975) Endocrinol. Japon, 22, 55

    Article  CAS  Google Scholar 

  33. Goldberg, N.D., O’dea, R.F. and Haddox, M.K., (1973), Adv. Cycl. Nucl. Res. 3 155

    CAS  Google Scholar 

  34. Seljelid, R. and Nakken, K.F., (1969), Scand. J. Clin. Lab. Invest. Suppl. 106, 125

    Google Scholar 

  35. Williams, J.A. (1972), Endocrinology, 90, 1459

    Article  PubMed  CAS  Google Scholar 

  36. Willems, C., Rocmans, P. and Dumont, J.E., (1971) Febs Letters, 14, 323

    Article  PubMed  CAS  Google Scholar 

  37. Grenier, G., Van Sande, J., Glick, D. and Dumont, J.E., (1974), Febs Letters, 49, 96

    Article  PubMed  CAS  Google Scholar 

  38. Rodesch, F., Bogaert, C. and Dumont J.E., (1974) Cptes Rend. Acad. Sci. ( Paris ) 278, 931

    CAS  Google Scholar 

  39. Yamashita, K. and Field, J.B., (1972) J. Biol. Chem., 247, 7062

    PubMed  CAS  Google Scholar 

  40. Barmasch, M., Pisarev, M.A. and Altschuler, N., (1973) Acta Endocr. Panam, 4, 19

    Google Scholar 

  41. Douglas, W.W., (1968), Brit. J. Pharmacol., 34, 451

    CAS  Google Scholar 

  42. Schultz, G., Hardman, J.G., Schultz, Kc, Baird, C.E. and Sutherland, E.W., (1973) Proceed. Natl. Acad. Sci., 70, 3889

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Institut de Recherche Interdisciplinaire, School of Medicine, University of Brussels and Biology Department, 1000, Euratom Brussels, Belgium

    J. E. Dumont, J. Van Sande, F. Lamy, R. Pochet & F. Rodesch

Authors
  1. J. E. Dumont
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. J. Van Sande
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. F. Lamy
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. R. Pochet
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. F. Rodesch
    View author publications

    You can also search for this author in PubMed Google Scholar

Editor information

Editors and Affiliations

  1. Institute of Interdisciplinary Research, University of Brussels Medical Schools, Brussels, Belgium

    Jacques E. Dumont

  2. Institute of Nuclear Medicine, Thorn Institute of Clinical Sciences, The Middlesex Hospital Medical School, London, UK

    Barry L. Brown  & Nicholas J. Marshall  & 

Rights and permissions

Reprints and permissions

Copyright information

© 1976 Plenum Press, New York

About this chapter

Cite this chapter

Dumont, J.E., Van Sande, J., Lamy, F., Pochet, R., Rodesch, F. (1976). The Regulation of Thyroid Cell Metabolism. In: Dumont, J.E., Brown, B.L., Marshall, N.J. (eds) Eukaryotic Cell Function and Growth. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-4322-6_35

Download citation

  • DOI: https://doi.org/10.1007/978-1-4613-4322-6_35

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4613-4324-0

  • Online ISBN: 978-1-4613-4322-6

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics

Search

Navigation