Abstract
The approach of our laboratory to the question of compartmentation in relation to structure and function of the brain has been to identify and characterize macro- and micromolecular markers of individual cell types in the mammalian CNS. Such biochemical markers could serve as monitors of function of specific cells and of their responses to changes in their immediate environment. We have, therefore, searched for examples of specific genetic expression by individual cell types, which could then enable us to study the functioning of a given cell in the midst of a complex mass of interacting neurons and glia. As an experimental model system we have chosen to study the olfactory bulb: receptor epithelium complex in vertebrates. This cerebral subsystem has several characteristics which make it a desirable model for studies ultimately oriented towards biochemical correlates of function.
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Margolis, F.L., Keller, A., Ferriero, D. (1975). The Olfactory Pathway as a Model Cerebral System. In: Berl, S., Clarke, D.D., Schneider, D. (eds) Metabolic Compartmentation and Neurotransmission. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-4319-6_8
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DOI: https://doi.org/10.1007/978-1-4613-4319-6_8
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