Cholesterol Ester: Lysolecithin Acyltransferase Activity of the Aorta

  • J. Patelski
  • M. Pioruńska
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 82)


Enzyme-catalyzed transfer from lecithin on cholesterol to form cholesterol ester and lysolecithin (LCAT+) 1/ in the arterial wall has been found (1) but not much is known about the reaction in reverse direction. It seemed to be of interest, therefore, to investigate the cholesterol ester: lysolecithin acy1 transfer activity (LCAT-) of the aortic wall, as compared with LCAT+ and cholesterol esterase activities.


Cholesterol Ester Aortic Wall Cholesterol Acyltransferase Ester Hydrolase Acyl Transfer 
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  1. 1.
    Abdulla, Y.H., Orton, C.C. and Adams, C.W.M., Cholesterol esterification by transacylation in human and experimental atheromatous lesions, J. Atheroseler. Res., 8 (1968) 967.CrossRefGoogle Scholar
  2. 2.
    Patelski, J., Pniewska, B., Pioruńska, M. and Obrebska, M., The arterial acyl-CoA: cholesterol acyltransferase and cholesterol ester hydrolase activities. In vitro effect of substrates with fatty acid of different chain length and saturation, Atherosclerosis, 22 (1975) 287–291.PubMedCrossRefGoogle Scholar
  3. 3.
    Patelski, J. and Pioruńska, M., Cholesterol ester:lysolecithin transacylation in the aorta, to be published.Google Scholar
  4. 4.
    Patelski, J., Participation of phospholipids in arterial metabolism of cholesterol esters, in this book.Google Scholar

Copyright information

© Plenum Press, New York 1977

Authors and Affiliations

  • J. Patelski
    • 1
  • M. Pioruńska
    • 1
  1. 1.Lipid Metabolism Laboratory, Department of BiochemistryMedical AcademyPoznańPoland

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