Cholesterol Ester: Lysolecithin Acyltransferase Activity of the Aorta
Enzyme-catalyzed transfer from lecithin on cholesterol to form cholesterol ester and lysolecithin (LCAT+) 1/ in the arterial wall has been found (1) but not much is known about the reaction in reverse direction. It seemed to be of interest, therefore, to investigate the cholesterol ester: lysolecithin acy1 transfer activity (LCAT-) of the aortic wall, as compared with LCAT+ and cholesterol esterase activities.
KeywordsCholesterol Ester Aortic Wall Cholesterol Acyltransferase Ester Hydrolase Acyl Transfer
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- 2.Patelski, J., Pniewska, B., Pioruńska, M. and Obrebska, M., The arterial acyl-CoA: cholesterol acyltransferase and cholesterol ester hydrolase activities. In vitro effect of substrates with fatty acid of different chain length and saturation, Atherosclerosis, 22 (1975) 287–291.PubMedCrossRefGoogle Scholar
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