The Effects of Fasting and Refeeding on in Vitro Lipogenesis and Glycogen Synthesis from U-14C-Glucose in the Rat Aorta

  • Kerin O’Dea
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 82)


Tissues of animals fasted for two to three days and subsequently refed a high carbohydrate diet exhibit an extremely high capacity for lipogenesis from non-fat precursors. This adaptive hyperlipogenesis of refeeding has been studied extensively in adipose tissue and liver and is associated with a number of striking changes in enzyme profiles. Increased circulating levels of insulin are considered to play a major role in this phenomenon.


Glycogen Synthesis Circulate Level High Carbohydrate Diet Cleveland Clinic Foundation Striking Change 
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Copyright information

© Plenum Press, New York 1977

Authors and Affiliations

  • Kerin O’Dea
    • 1
  1. 1.Research DivisionCleveland Clinic FoundationClevelandUSA

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