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Chylomicron Remnant Particle Formation In Vivo in Hepatectomised Rat

  • A. Vost
  • D. M.-E. Pocock
  • S. Pleet
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 82)

Abstract

The triglyceride-rich lipoproteins, chylomicrons and very low density lipoproteins, are initially catabolised by enzymatic removal of part of their triglyceride mass in extrahepatic tissues (1). Subsequently the cholesteryl esters and part of the cholesterol retained in the chylomicron remnant particles are cleared from plasma by liver; in the hepatectomised rat chylomicron triglyceride is cleared but chylomicron cholesterol and cholesteryl esters accumulate in plasma in particles with an apparent mean diameter approximately half that of their precursor chylomicrons (2).

Keywords

Cholesteryl Ester High Density Lipoprotein Extrahepatic Tissue Enzymatic Removal Montreal General Hospital 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. (1).
    HAVEL, R. J. In Handbook of Physiology, Section 5, American Physiological Society, Washington D.C., 499–507 (1965).Google Scholar
  2. (2).
    REDGRAVE, T. G., J. Clin. Invest. 49, 465–471 (1970).PubMedCrossRefGoogle Scholar
  3. (3).
    RUDEL, L. L., J. A. LEE, M. M. MORRIS and J. M. FELTS, Biochem. J. 139, 89–95 (1974).PubMedGoogle Scholar

Copyright information

© Plenum Press, New York 1977

Authors and Affiliations

  • A. Vost
    • 1
  • D. M.-E. Pocock
    • 1
  • S. Pleet
    • 1
  1. 1.McGill University Medical ClinicThe Montreal General HospitalMontrealCanada

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