Chylomicron Remnant Particle Formation In Vivo in Hepatectomised Rat
The triglyceride-rich lipoproteins, chylomicrons and very low density lipoproteins, are initially catabolised by enzymatic removal of part of their triglyceride mass in extrahepatic tissues (1). Subsequently the cholesteryl esters and part of the cholesterol retained in the chylomicron remnant particles are cleared from plasma by liver; in the hepatectomised rat chylomicron triglyceride is cleared but chylomicron cholesterol and cholesteryl esters accumulate in plasma in particles with an apparent mean diameter approximately half that of their precursor chylomicrons (2).
KeywordsCholesteryl Ester High Density Lipoprotein Extrahepatic Tissue Enzymatic Removal Montreal General Hospital
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- (1).HAVEL, R. J. In Handbook of Physiology, Section 5, American Physiological Society, Washington D.C., 499–507 (1965).Google Scholar