Experimental Investigation of Hypolipidemic and Anti-Atherosclerotic Drugs with Different Mechanism of Action
In the Soviet Union the following drugs are used to reduce the plasma level of cholesterol and triglycerides in patients with hyperlipidemias: miscleron (Clofibrate), nicotinic acid, β-sitosterol and the preparations containing unsaturated fatty acids. Amongst them there are arachiden and conlitol. Arachiden is a mixture of ethyl esters of arachidonic, linoleic, linolenic, pentaene and hexaene acids. It is prepared from the lipid fraction of cattle pancreas. Conlitol is a mixture of ethyl esters of unsaturated fatty acids isolated from linseed oil. Both preparations are used orally.
KeywordsCholesterol Permeability Ethyl Polysaccharide Triglyceride
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