Experimental Investigation of Hypolipidemic and Anti-Atherosclerotic Drugs with Different Mechanism of Action

  • A. N. Klimov
  • V. E. Ryzhenkov
  • L. A. Petrova
  • E. D. Polyakova
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 82)

Abstract

In the Soviet Union the following drugs are used to reduce the plasma level of cholesterol and triglycerides in patients with hyperlipidemias: miscleron (Clofibrate), nicotinic acid, β-sitosterol and the preparations containing unsaturated fatty acids. Amongst them there are arachiden and conlitol. Arachiden is a mixture of ethyl esters of arachidonic, linoleic, linolenic, pentaene and hexaene acids. It is prepared from the lipid fraction of cattle pancreas. Conlitol is a mixture of ethyl esters of unsaturated fatty acids isolated from linseed oil. Both preparations are used orally.

Keywords

Cholesterol Permeability Ethyl Polysaccharide Triglyceride 

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Copyright information

© Plenum Press, New York 1977

Authors and Affiliations

  • A. N. Klimov
    • 1
  • V. E. Ryzhenkov
    • 1
  • L. A. Petrova
    • 1
  • E. D. Polyakova
    • 1
  1. 1.Institute for Experimental Medicine of the USSRLeningradUSSR

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