Renal Tubular Handling of 3′,5′ — cAMP in Normal and Parathyroidectomized Rats

  • H. Kuntziger
  • H. L. Cailla
  • C. Amiel
  • M. A. Delaage
Part of the Advances in Experimental Medicine and Biology book series (AEMB)

Abstract

Urinary excretion exceeding filtered load indicates net tubular addition of 3′,5′ — cAMP in normal mammals. Tubular addition of the nucleotide depends on parathyroid hormone. This study investigated:
  1. 1.

    the nephron segment where 3′,5′- cAMP addition occurs,

     
  2. 2.

    a possible reabsorptive transport participating in net overall renal handling,

     
  3. 3.

    the localization of the altered tubular transport induced by parathyroidectomy (PTX).

     

Keywords

Adenosine Monophosphate 

References

  1. 1.
    Amiel, C., Kuntziger, H., and Richet, G.: Micropuncture study handling of phosphate by proximal and distal nephron in normal and parathyroidectomized rat. Evidence for distal reabsorption. Pflügers Arch. 317: 93, 1970.PubMedCrossRefGoogle Scholar
  2. 2.
    Cailla, H.L., Racine-Weisbuch, M.S., and Delaage, M.A.: Adenosine 3′,5′- cyclic monophosphate assay at 10-15 Mole level. Anal. Biochem. 56: 394, 1973.PubMedCrossRefGoogle Scholar

Copyright information

© Springer Science+Business Media New York 1977

Authors and Affiliations

  • H. Kuntziger
    • 1
    • 2
  • H. L. Cailla
    • 1
    • 2
  • C. Amiel
    • 1
    • 2
  • M. A. Delaage
    • 1
    • 2
  1. 1.Inserm U. 64Hopital TenonParisFrance
  2. 2.CBBMCNRSMarseilleFrance

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