Abstract
Immune response in chickens to the multi-chain copolymer (T, G)-A—L 2o3o is analysed. Previous work has shown that responsiveness is not linked to the B-complex. Three different antibody specificities could be distinguished. From the data it is proposed that the response to the backbone of (T, G)-A—L (poly-DL-alanine) influences the responses to the side chain determinants (primarily the (T, G)-determinant). Thus the anti-(T,G) response in chickens is determined by at least two different loci, the B-complex, and another, as yet unidentified locus which determines the response to the poly-DL- alanine determinant. A third antibody specificity is directed against G-A—L and is only detectable in chickens which are high responders to poly-DL-alanine.
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© 1977 Plenum Press, New York
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Koch, C., Hála, K., Sørup, P. (1977). Immune Response Genes in Chickens: The Multifarious Responsiveness to (T, G)-A--L. In: Benedict, A.A. (eds) Avian Immunology. Advances in Experimental Medicine and Biology, vol 88. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-4169-7_22
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DOI: https://doi.org/10.1007/978-1-4613-4169-7_22
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