Screening by Gas Chromatography-Mass Spectrometry for Metabolites of Five Commonly Used Anabolic Steroid Drugs

  • R. J. Ward
  • A. M. Lawson
  • C. H. L. Shackleton


A gas chromatographic-mass spectrometry (GC-MS) technique is described for the detection and identification of anabolic steroid drugs in urine samples of athletes competing in major international events.

The metabolism of some commonly used drugs, in particular, Dianabol (17α-methyl-1,4-androstadien-17ß-o1-3-one), Stanazolol (17α-methyl-5α-androstan-17ß-o1-[ 3,2-c ]-pyrazole), Nilevar (17α-ethyl-4-estren-17ß-o1-3-one), Orabolin (17α-ethyl-4-estren-17ß-o1), Durabolin (4-estren-17ß-o1-3-one phenylpropionate) have been studied. The approach to processing the data from the GC-MS analysis does not preclude the detection of other additional anabolic steroid drugs.


Anabolic Steroid Endogenous Steroid Sport Federation Anabolic Drug Repetitive Scanning 


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Copyright information

© Plenum Press, New York 1977

Authors and Affiliations

  • R. J. Ward
    • 1
  • A. M. Lawson
    • 1
  • C. H. L. Shackleton
    • 1
  1. 1.Division of Clinical ChemistryClinical Research CentreHarrow, MiddlesexEngland

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