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Calcification and Fibrosis of Mitral Valves: In Vitro Ultrasonic Studies and Clinical Correlations

  • R. G. Schwartz
  • N. C. Nanda
  • R. Gramiak

Abstract

In the present study, M-mode echocardiography has been used to correlate specific echo patterns produced in vitro by calcified and non-calcified mitral valves with the degree of calcification of the valves. The extent of calcification and fibrosis of each mitral valve was readily determined by gross pathological examination, low-exposure x-rays to maximize differential tissue density resolution, and in 2 valves by microscopic examination. Using these techniques we found that 7 of 9 diseased, surgically excised mitral valves in this series showed evidence of solid, readily identifiable areas of moderate to heavy calcification and diffuse thickening, whereas 2 valves showed zero to trace amounts of either calcium or fibrosis. A tenth valve obtained at autopsy was added to this series and was found to be normal, without calcification or fibrosis, and served as a normal control.

Keywords

Mitral Valve Gain Setting Discrete Line Ultrasonic Study Rochester Medical 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Copyright information

© American Institute of Ultrasound in Medicine and Plenum Press, New York 1978

Authors and Affiliations

  • R. G. Schwartz
    • 1
  • N. C. Nanda
    • 1
  • R. Gramiak
    • 1
  1. 1.Departments of Medicine (Cardiology Unit) and RadiologyThe University of Rochester School of Medicine and Dentistry, University of Rochester Medical CenterRochesterUSA

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