Calcification and Fibrosis of Mitral Valves: In Vitro Ultrasonic Studies and Clinical Correlations

  • R. G. Schwartz
  • N. C. Nanda
  • R. Gramiak

Abstract

In the present study, M-mode echocardiography has been used to correlate specific echo patterns produced in vitro by calcified and non-calcified mitral valves with the degree of calcification of the valves. The extent of calcification and fibrosis of each mitral valve was readily determined by gross pathological examination, low-exposure x-rays to maximize differential tissue density resolution, and in 2 valves by microscopic examination. Using these techniques we found that 7 of 9 diseased, surgically excised mitral valves in this series showed evidence of solid, readily identifiable areas of moderate to heavy calcification and diffuse thickening, whereas 2 valves showed zero to trace amounts of either calcium or fibrosis. A tenth valve obtained at autopsy was added to this series and was found to be normal, without calcification or fibrosis, and served as a normal control.

Keywords

Conglomerate 

Copyright information

© American Institute of Ultrasound in Medicine and Plenum Press, New York 1978

Authors and Affiliations

  • R. G. Schwartz
    • 1
  • N. C. Nanda
    • 1
  • R. Gramiak
    • 1
  1. 1.Departments of Medicine (Cardiology Unit) and RadiologyThe University of Rochester School of Medicine and Dentistry, University of Rochester Medical CenterRochesterUSA

Personalised recommendations