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Burkitt’s Lymphoma and Infectious Mononucleosis

  • Dennis H. Wright
Part of the Comprehensive Immunology book series (COMIMUN, volume 4)

Abstract

Two apparently disparate diseases form the subject of this chapter: infectious mononucleosis, an acute and usually self–limiting disease of adolescence and young adult life, and Burkitt’s lymphoma, a rapidly progressive malignant lymphoma of children and occasionally of young adults that shows remarkable epidemiological features. The link between these two entities is the Epstein–Barr virus, which is now known to be the causative agent of infectious mononucleosis and is suspected of having a major etiological role in Burkitt’s lymphoma. Following a presentation of the evidence linking the Epstein–Barr virus with infectious mononucleosis and Burkitt’s lymphoma, one of the objectives of this chapter will be to explore the ways in which a single agent, if indeed the Epstein–Barr virus is a single agent, can evoke such different responses in different hosts.

Keywords

Malignant Lymphoma Lymphoblastoid Cell Line Infectious Mononucleosis Sickle Cell Trait Geometric Mean Titer 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Plenum Publishing Corporation 1978

Authors and Affiliations

  • Dennis H. Wright
    • 1
  1. 1.University of Southampton Medical SchoolSouthamptonEngland

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