Abstract
The carotid body is a peripheral arterial chemoreceptor which senses arterial blood pH, PC0 2 and P0 2. Neuronal activity from the carotid body is conveyed to the central nervous system by the carotid sinus nerve, a branch of the ninth cranial nerve. In 1968 Biscoe and Sampson1 recorded neuronal activity from the central end of the sinus nerve. This activity was of two types. The first type displayed a respiratory rhythm in firing rate and was shown to arise from the sympathetic nervous system via the superior cervical ganglion. The second type appeared to originate directly from the central nervous system and displayed a random firing pattern. This second type of activity is termed sinus nerve efferent activity, and has been shown by Sampson and Biscoe2 and by Neil and O’Regan3, 4 to be capable of inhibiting carotid chemoreceptor afferent activity. We have investigated the response of sinus nerve efferent activity to changes in systemic arterial pressure induced passively by bleeding and by reinfusion of the animal’s own blood. Some of these results have been presented to the Physiological Society5.
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References
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© 1978 Plenum Press, New York
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Willshaw, P., Majcherczyk, S. (1978). The Effects of Changes in Arterial Pressure on Sinus Nerve Efferent Activity. In: Fitzgerald, R.S., Gautier, H., Lahiri, S. (eds) The Regulation of Respiration During Sleep and Anesthesia. Advances in Experimental Medicine and Biology, vol 99. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-4009-6_30
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DOI: https://doi.org/10.1007/978-1-4613-4009-6_30
Publisher Name: Springer, Boston, MA
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