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Isolation and Identification of Oxidized Metabolites of Phenazopyridine from Rat Urine

  • D. Pitrè
  • R. Maffei-Facino
  • R. Tonani

Abstract

Until recently all reports in the literature on the urinary metabolites of phenazopyridine (2,6-diamino-3-(phenylazopyridine)), a drug widely used for analgesia of the lower urinary tract (1), indicated that the in vivo metabolism involved reduction and splitting off the azo linkage. These metabolites included 2,3,6-triaminopyridine, aniline, 4-aminophenol, 2-aminophenol and 4-acetamidophenol (2, 3).

Keywords

Lower Urinary Tract Acetic Anhydride Butyl Acetate Aqueous Residue Direct Injection System 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Plenum Press, New York 1978

Authors and Affiliations

  • D. Pitrè
    • 1
  • R. Maffei-Facino
    • 2
  • R. Tonani
    • 2
  1. 1.Bracco Industria ChimicaFarmaceuticaItaly
  2. 2.Istituto ChimicaFarmaceuticaItaly

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