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Metabolic Profile of Biological Constituents: (1) The Effects of Sodium Dipropylacetate on Human Urinary Acids

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Recent Developments in Mass Spectrometry in Biochemistry and Medicine

Abstract

In order to evaluate drugs, investigation of absorption, biotransformation, excretion, biological action and therapeutic application in humans is essential. However, the principle for the evaluation should be based on an understanding of the interrelations between drugs and human bodies.

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References

  1. E.C. Horning and M.G. Horning, Clin. Chem., 1971, 17, 802.

    Google Scholar 

  2. J.A. Thompson and S.P. Markey, Anal. Chem., 1975, 47, 1313.

    Article  Google Scholar 

  3. I. Horman and F.J. Hesford, Biomed. Mass Spectrom., 1974, 1, 115.

    Article  Google Scholar 

  4. S.P. Markey, W.G. Urban and S.P. Levine, Eds., “Mass spectra of compounds of biological interest”, National Technical Information Service, U.S. Department of Commerce, Springfield, Virginia, 1974.

    Google Scholar 

  5. R.F. Coward and P. Smith, J. Chromatogr., 1969, 45, 230.

    Article  Google Scholar 

  6. S. Landaas, Clin. Chim. Acta, 1975, 64, 143.

    Article  Google Scholar 

  7. T. Kuhara and I. Matsumoto, Biomed. Mass Spectrom., 1974, 291.

    Google Scholar 

  8. I. Matsumoto, T. Kuhara and M. Yoshino, Biomed. Mass Spectrom., 1976, 3, 235.

    Article  Google Scholar 

  9. T. Ando, K. Rasmussen, W.L. Nyhan and D. Hull, Proc. Nat. Acad. Sci. USA, 1972, 69, 2807.

    Google Scholar 

  10. O.A. Mamer and S.S. Tjoa, Clin. Chim. Acta, 1974, 55, 199.

    Article  Google Scholar 

  11. O.A. Mamer and S.S. Tjoa, Biomed. Mass Spectrom., 1975, 2, 133.

    Google Scholar 

  12. O.A. Mamer and S.S. Tjoa, Biomed. J., 1976, 160, 417.

    Google Scholar 

  13. J. Diekman, J.B. Thomson and C. Djerassi, J. Org. Chem., 1967, 32, 3904.

    Article  Google Scholar 

  14. T. Ando, K. Rasmussen, W.L. Nyhan, G.N. Donnel and N.D. Barnes, J. Pediatr., 1971, 78, 827.

    Article  Google Scholar 

  15. K. Kukino and T. Deguchi, Chem. Pharm. Bull., 1977, in press.

    Google Scholar 

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© 1978 Plenum Press, New York

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Kuhara, T., Iwai, Y., Haraguchi, S., Shinka, T., Matsumoto, I. (1978). Metabolic Profile of Biological Constituents: (1) The Effects of Sodium Dipropylacetate on Human Urinary Acids. In: Frigerio, A. (eds) Recent Developments in Mass Spectrometry in Biochemistry and Medicine. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-3991-5_15

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  • DOI: https://doi.org/10.1007/978-1-4613-3991-5_15

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4613-3993-9

  • Online ISBN: 978-1-4613-3991-5

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