• Toshiji Kobayashi


The discovery by the Curie brothers in 1880 of the piezoelectric effect was the first step toward today’s blossoming of the use of diagnostic ultrasound all over the world. The practical application of this basic piezoelectric principle was first introduced by Chilowsky and Langevin in 1916 for submarine detection during the first World War, for industrial work as a flaw detector in metals by Sokolov in 1937, and finally, for use in the medical field by the Austrian, Dr. Dussik in 1942 to delineate brain tumors. Ultrasonic echography was found to offer considerable potential as a diagnostic technique for the visualization of soft tissue structures—especially for the differential diagnosis of breast cancer. Table 1 summarizes in chronological order the milestones and epoch-making events associated with the development of instrumentation and methods for the differential diagnosis of breast tumors by ultrasonic echography.


Papillary Carcinoma Medullary Carcinoma Distal Limit Ultrasonic Attenuation Scirrhous Carcinoma 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Plenum Publishing Corporation 1978

Authors and Affiliations

  • Toshiji Kobayashi
    • 1
  1. 1.National Cancer Center HospitalTokyoJapan

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