Far more abundant use has been made in psychopharmacology of strains of rats (especially), which were created by selective breeding but for some phenotype, usually a behavioral one, other than the psychopharmacological ones we have hitherto been considering. Usually such selections have been made bidirectionally and hence their use in this connection constitutes a special case of the more general approach to psychogenetics via the study of strain differences. Mention has already been made (see Chapter 3) of the Tyron rat strains, the maze-bright and -dull (TMB and TMD), and consideration of contributions based on their use is given pride of place.
KeywordsPlacebo Cocaine Caffeine Acetylcholine Chlordiazepoxide
Unable to display preview. Download preview PDF.