On the Pathogenicity of Avian Influenza Viruses

  • Rudolf Rott
  • Hans-Dieter Klenk
  • Christoph Scholtissek
Part of the Developments in Molecular Virology book series (DMVI, volume 3)


Influenza A viruses cause different diseases in mammals and birds. While the clinical manifestations of influenza virus infection in mammals is virtually always a result of localized infection of the respiratory tract epithelium, the clinical disease in birds infected with highly pathogenic avian influenza viruses is commonly associated with systemic infection and death. The majority of avian influenza viruses, however, induce asymptomatic infection which is restricted to local sites in mucous membranes frequently in the gut and the respiratory tract.


Influenza Virus Avian Influenza Virus Influenza Virus Infection Gene Constellation Nonpathogenic Strain 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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  1. 1.
    Hinshaw, V.S., Webster, R.G. and Rodriguez, R.J. Arch. Virol. 67: 191–201, 1981.PubMedCrossRefGoogle Scholar
  2. 2.
    Hinshaw, V.S., Air, G.M., Gibbs, A.J., Graves, L., Pres- cott, R. and Karunakaran, D. J. Virol. 42: 865–872, 1982.PubMedGoogle Scholar
  3. 3.
    Scholtissek, C. In: Genetics of Influenza Viruses, Viro¬logy Monographs (Ed. P. Palese) Springer-Verlag, Wien, 1983, in press.Google Scholar
  4. 4.
    Easterday, B.C. In: The Influenza Viruses and Influenza (Ed. E.D. Kilbourne) Academic Press, New York, 1975, pp. 449–481.Google Scholar
  5. 5.
    Rott, R., Huang, R.T.C., Wahn, K. and Klenk, H.-D. In: Replication of Negative Strand Viruses (Eds. D.H.L. Bishop and R.W. Compans ), Elsevier/North Holland, New York, 1981, pp. 269–276.Google Scholar
  6. 6.
    Klenk, H.-D. and Rott, R. Curr. Top. Microbiol. Immunol. 90: 19–48, 1980.PubMedGoogle Scholar
  7. 7.
    Schulman, J.L. and Palese, P. J. Virol. 24: 170–176, 1977.PubMedGoogle Scholar
  8. 8.
    Klenk, H.-D., Rott, R., Orlich, M. and Blödorn, J. Virology 68: 426–439, 1975.PubMedCrossRefGoogle Scholar
  9. 9.
    Bosch, F.X., Orlich, M., Klenk, H.-D. and Rott, R. Virology 95: 197–207, 1979.PubMedCrossRefGoogle Scholar
  10. 10.
    Rott, R., Orlich, M. and Scholtissek, C. Virology 120: 215–224, 1982.PubMedCrossRefGoogle Scholar
  11. 11.
    Ward, C.W. Curr. Top. Microbiol. Immunol. 94: 1–74, 1981.PubMedGoogle Scholar
  12. 12.
    Porter, A.G., Barber, C., Carey, N.H., Hallewell, P.A., Threlfall, G. and Emtage, J.S. Nature (London) 282: 471– 477, 1979.Google Scholar
  13. 13.
    Garten, W., Linder, D., Rott, R. and Klenk, H.-D. Virology 122: 186–190, 1982.PubMedCrossRefGoogle Scholar
  14. 14.
    Bosch, F.X., Garten, W., Klenk, H.-D. and Rott, R. Virology 113: 725–735, 1981.PubMedCrossRefGoogle Scholar
  15. 15.
    Garten, W., Bosch, F.X., Linder, D., Rott, R. and Klenk, H.-D. Virology 115: 36l–374, 1981.CrossRefGoogle Scholar
  16. 16.
    Rott, R., Reinacher, M., Orlich, M. and Klenk, H.-D. Arch. Virol. 65: 123–133, 1980.PubMedCrossRefGoogle Scholar
  17. 17.
    Webster, R.G., Campbell, C.H. and Granoff, A. Virology 44: 317–328, 1971.PubMedCrossRefGoogle Scholar
  18. 18.
    Rott, R. and Scholtissek, C. In: Basic and Applied Influenza Research (Ed. A.S. Beare ), CRC Press, Inc., Boca Raton, 1982, pp. 189–210.Google Scholar
  19. 19.
    Rott, R. Arch. Virol. 59: 285–298, 1979.PubMedCrossRefGoogle Scholar
  20. 20.
    Rott, R., Orlich, M. and Scholtissek, C. Virology 126: 1983, in press.Google Scholar
  21. 21.
    Sivasubramanian, N. and Nayak, D.P. Virology 124: 232–237, 1983.PubMedCrossRefGoogle Scholar

Copyright information

© Martinus Nijhoff Publishing, Boston 1984

Authors and Affiliations

  • Rudolf Rott
    • 1
  • Hans-Dieter Klenk
    • 1
  • Christoph Scholtissek
    • 1
  1. 1.Institut für VirologieJustus-Liebig-Universität GiessenGiessenGermany

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