Association of oocytes with follicle cells, and oocyte chromatin during maturation

  • Robert W. McGaughey
Part of the Electron Microscopy in Biology and Medicine book series (EMBM, volume 2)


Immature mammalian oocytes are derived from primordial germ cells (PGCs) which have migrated to the developing embryonic ovary. These cells proliferated mitotically as oogonia and entered meiotic prophase. In this chapter, the term immature oocyte refers to those stages of female gametogenesis in which the nucleus is at the diplotene stage of meiosis. The diplotene stage is reached in mammalian oocytes at or about the time of parturition. The nuclear stage, germinal vesicle (GV), present in these immature primary oocytes persists to the adult stage. Meiosis is arrested at the GV stage. Resumption of arrested meiosis occurs in the sexually mature female.


Granulosa Cell Follicular Fluid Oocyte Maturation Zona Pellucida Cumulus Cell 
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Copyright information

© Martinus Nijhoff Publishers, Boston, The Hague, Dordrecht, Lancaster 1984

Authors and Affiliations

  • Robert W. McGaughey
    • 1
  1. 1.Department of ZoologyArizona State UniversityTempeUSA

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