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Ultrastructural changes in ovarian oocytes induced by exposure to ionizing radiations

  • Terry G. Baker
  • Leslie L. Franchi
Part of the Electron Microscopy in Biology and Medicine book series (EMBM, volume 2)

Abstract

The transmission electron microscope has proved to be a most useful tool to the biologist and over the past twenty five years it has been used to explore the fine structure of a wide variety of cellular types and their organelles. The internal anatomy of the cell varies with function and characteristic changes are detectable by microscopy when its physiology and biochemistry become altered. It is therefore surprising that there have been few studies concerned with the ultrastructure of radiation damage, since this results from changes in cellular biochemistry (1–3). It will be shown in this chapter, however, that electron microscopy has provided little meaningful information about either the nature of the primary lesion or the sequence of events leading to radiation-induced cell death. It can be argued that a major reason for the paucity of such studies is the very complexity of the problem itself. Radiation biology is a complex interdisciplinary subject bridging large areas of physics, chemistry, biology and medicine. As a subject it is thwart with difficulties owing to the diversity of cell types and of processes of differentiation.

Keywords

Germ Cell Granulosa Cell Follicle Cell Primordial Follicle Primordial Germ Cell 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Martinus Nijhoff Publishers, Boston, The Hague, Dordrecht, Lancaster 1984

Authors and Affiliations

  • Terry G. Baker
    • 1
  • Leslie L. Franchi
    • 2
  1. 1.School of Medical SciencesUniversity of BradfordBradfordUK
  2. 2.Department of AnatomyUniversity of BirminghamBirminghamUK

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