Platelet Transfusion Therapy for Patients with Cancer

  • Charles A. Schiffer
Part of the Cancer Treatment and Research book series (CTAR, volume 13)


A number of important advances have occurred in the area of platelet transfusion therapy in recent years. As recently as 10 years ago, the greatest problem in many centers was simply obtaining sufficient numbers of units of platelets for the increasing population of patients with cancer and leukemia being treated more intensively and successfully with newer chemotherapeutic agents. Improvements in bag design and plastics, an increased understanding of the many factors which influence platelets during storage, the development of sophisticated and well organized hospital and regional blood centers and the proliferation of apheresis equipment in these centers, have all helped to make platelets readily available in almost all medical centers. Different problems have arisen however which still limit the effectiveness of platelet transfusions in many patients. In particular, the provision of histocompatible platelets for alloimmunized patients remains a difficult and expensive challenge, and this issue and others will be discussed in this review.


Disseminate Intravascular Coagulation Platelet Transfusion Platelet Storage Prophylactic Platelet Transfusion Lymphocytotoxic Antibody 
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© Martinus Nijhoff Publishers, Boston 1983

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  • Charles A. Schiffer

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