Immunologic Considerations of Patients with Brain Tumors

  • M. S. MahaleyJr.
  • G. Yancey Gillespie
Part of the Cancer Treatment and Research book series (CTAR, volume 12)

Abstract

Continued interest in the immunologic considerations of patients with malignant gliomas stems from the frustration that clinicians face in current concepts of management coupled with the attractiveness of the hypothetical, selective destruction of malignant cells by elements of the immune system. Our frustration with current therapies is exemplified by the fact that the most effective combinations of surgery, radiotherapy, and chemotherapy for malignant gliomas only increases the median survival time from 17 weeks for patients untreated postoperatively to a little over a year for optimally treated patients [1]. The attractiveness of mobilizing the immune system to control neoplasia has undoubtedly been promoted by the recognized cellular immune responses that all too successfully result in transplantation rejections together with the humoral (antibody) immune mechanisms responsible for specific and timely neutralization and destruction of microbial invaders.

Keywords

Influenza Oncol Neurol Myeloma Meningioma 

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Copyright information

© Martinus Nijhoff Publishers, Boston/The Hague/Dordrecht/Lancaster 1983

Authors and Affiliations

  • M. S. MahaleyJr.
  • G. Yancey Gillespie

There are no affiliations available

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