Abstract
Local control of extremity soft-tissue sarcomas is still a significant and important clinical problem. Although surgical procedures have been extended from simple excisions to more radical and super-radical amputative procedures, the local recurrence rate for both the skeletal and soft-tissue sarcomas remains high and in most series approaches 20–30% if treatment is surgery alone (1–6). Because local recurrence of these highly malignant tumors usually foretells poor prognosis, the local control of these lesions becomes an important consideration. Megavoltage radiation therapy, the delivery of high doses of external beam radiation, just after the following surgical procedures has reduced the local recurrence rate to approximately 15–20% and improved the overall survival (7–9).
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© 1984 Martinus Nijhoff Publishers, Boston
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Eilber, F.R., Mirra, J., Eckardt, J., Kern, D. (1984). Intraarterial Adriamycin, Radiation Therapy, and Surgical Excision for Extremity Skeletal and Soft-Tissue Sarcomas. In: Howell, S.B. (eds) Intra-Arterial and Intracavitary Cancer Chemotherapy. Developments in Oncology, vol 26. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-3843-7_13
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DOI: https://doi.org/10.1007/978-1-4613-3843-7_13
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