New Approaches to the Use of Endocrine Therapy in Breast Cancer
Endocrine therapy has become more important in recent years in the management of breast cancer because of its lack of toxicity and consequent excellent remissions that it can sometimes provide. Furthermore, the oestrogen receptor assay can, to a certain extent, predict which patients will respond to therapy, thus reinforcing the need for a reappraisal of our strategy in selecting agents for clinical use and in defining their mechanism of action. Improved knowledge of mechanisms should lead to rational combinations which could lead to increased response rates and prolonged survival for patients with breast cancer.
KeywordsBreast Cancer Endocrine Therapy Mammary Tumour Advanced Breast Cancer Medroxyprogesterone Acetate
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- 2.Williams JC, Singh D, Brodie A, Coombes RC: Endocrine agents and their effect in rats bearing NMU-induced mammary tumours. (In preparation).Google Scholar
- 3.Brodie A: Personal Communication.Google Scholar
- 6.Coombes RC, Powles TJ, Muindi J, Hunt J, Ward M, Perez D, Neville AM: Trilostane therapy for advanced breast cancer. In Press.Google Scholar