New Approaches to the Use of Endocrine Therapy in Breast Cancer

  • R. C. Coombes
  • J. Williams
  • A. Brodie
  • T. J. Powles
  • A. M. Neville
Part of the Developments in Oncology book series (DION, volume 23)

Abstract

Endocrine therapy has become more important in recent years in the management of breast cancer because of its lack of toxicity and consequent excellent remissions that it can sometimes provide. Furthermore, the oestrogen receptor assay can, to a certain extent, predict which patients will respond to therapy, thus reinforcing the need for a reappraisal of our strategy in selecting agents for clinical use and in defining their mechanism of action. Improved knowledge of mechanisms should lead to rational combinations which could lead to increased response rates and prolonged survival for patients with breast cancer.

Keywords

Toxicity Oncol Tamoxifen Oestradiol Hunt 

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Copyright information

© Martinus Nijhoff Publishing, Boston 1984

Authors and Affiliations

  • R. C. Coombes
  • J. Williams
  • A. Brodie
  • T. J. Powles
  • A. M. Neville

There are no affiliations available

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