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The Management of Nausea and Vomiting Caused by Anticancer Chemotherapy

  • Christopher J. Williams
Part of the Developments in Oncology book series (DION, volume 23)

Abstract

Although other side effects of cytotoxic therapy are potentially more serious and can be life threatening, nausea and vomiting is by far the most unpleasant toxicity from the patients’ perspective. It may be severe enough to cause some patients to default treatment, even when they have a potentially curable tumour. However, the neuropharmacology of emesis is extremely complicated and not fully understood. The way the cytotoxic drugs induce ones is is variable and different antiemetics have different modes of action. When it is also remembered that cytotoxics are commonly used in combinations of 3 or 4 drugs and that studies of antiemetics to prevent chemotherapy associated emesis are a recent phenomenon (table 1), it is not surprising that no definitive statements can be made about the best ways to manage it. This chapter reviews the current state of the art.

Keywords

Cancer Chemotherapy Motion Sickness Cytotoxic Therapy Antiemetic Effect Antiemetic Regime 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Martinus Nijhoff Publishing, Boston 1984

Authors and Affiliations

  • Christopher J. Williams

There are no affiliations available

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