Excitation-Contraction in Cardiac Muscle of the Adult and Senescent Rat

  • Edward G. Lakatta
Part of the Developments in Cardiovascular Medicine book series (DICM, volume 42)


The impact of adult aging on many aspects of myocardial function in animals and man has recently been reviewed (1,2,3). The present discussion will focus on excitation-contraction and aging of the myocardium. I will try -to integrate the findings of recent and earlier studies in order to formulate alternative hypotheses regarding the mechanisms of age-related alterations of excitation-contraction coupling.


Sarcoplasmic Reticulum Rest Membrane Potential Contraction Duration Develop Tension Transmembrane Action Potential 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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© Martinus Nijhoff Publishing, Boston 1984

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  • Edward G. Lakatta

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