The Interferon System in Man: Nature of the Interferon Molecules and Mode of Action

  • Michel Revel
Part of the Developments in Molecular Virology book series (DMVI, volume 4)

Abstract

The task of describing the human IFN system in 1983 has been simultaneously enormously simplified and enormously complicated. The results of the past 3 years on the cloning of IFN cDNA and genes have told us the aminoacid sequence of human IFN-α, β and γ, but have also indicated the existence of multiple IFN subspecies, which are synthesized by various cells under various conditions. Even though the sequence of many IFN is known, the basis for the nomenclature of the 3 IFN classes α (leucocyte), β (fibroblast) and γ (immune), is still the immunoneutralization by specific antibodies.

Keywords

Hepatitis Aspirin Oncol Prostaglandin Prolactin 

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Copyright information

© Martinus Nijhoff Publishing, Boston 1984

Authors and Affiliations

  • Michel Revel
    • 1
  1. 1.Department of VirologyThe Weizmann Institute of ScienceRehovotIsrael

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