In Utero Induction of Sister Chromatid Exchanges to Detect Transplacental Carcinogens

  • R. K. Sharma
  • M. Lemmon
  • J. Bakke
  • I. Galperin
  • D. Kram
Part of the Environmental Science Research book series (ESRH, volume 29)

Abstract

Analysis of sister chromatid exchanges (SCEs) is proving to be a sensitive technique for detecting mutagens and carcinogens. To assess the transplacental carcinogenic potential of chemicals, we are evaluating SCE induction in developing fetuses exposed in utero to known carcinogens.

Keywords

Dine Phosphamide Ethylnitrosourea 

Copyright information

© Plenum Press, New York 1983

Authors and Affiliations

  • R. K. Sharma
    • 1
  • M. Lemmon
    • 1
  • J. Bakke
    • 1
  • I. Galperin
    • 1
  • D. Kram
    • 2
  1. 1.SRI InternationalMenlo ParkUSA
  2. 2.U.S. Environmental Protection AgencyUSA

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