Abstract
The activities of the immune system are customarily divided into specific functions mediated by immunoglobulin, and a range of other functions which are loosely classed by “non-specific”. Many of these latter do however exhibit a degree of specificity. Thus phagocytic cells can recognise and engulf a variety of foreign particles and yet ignore host cells, natural killer cells will lyse certain targets and not others; and, as will be mentioned later, there are grounds for supposing that there is some specificity in the recognition of different adjuvants. The purpose of this paper is to bring together some diverse observations which appear to be moving towards the identification of a system of non-immunoglobulin molecules as being responsible for some low-specificity recognition phenomena, and to focus on the question of whether adjuvanticity is, like antigenicity, recognised by specific receptors.
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© 1983 Plenum Press, New York
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Taylor, R.B., Morrison, C.A. (1983). How is Adjuvanticity Recognised?. In: Celada, F., Schumaker, V.N., Sercarz, E.E. (eds) Protein Conformation as an Immunological Signal. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-3778-2_38
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DOI: https://doi.org/10.1007/978-1-4613-3778-2_38
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