Solar Urticaria

  • Warwick L. Morison

Abstract

Solar urticaria is a disease in which a person develops hives during or immediately after exposure to nonionizing electromagnetic radiation contained in the solar spectrum. The urticaria is restricted to the site of exposure, but systemic symptoms such as headache and malaise can accompany it. Solar urticaria was first described as a distinct clinical entity in 1905 by Ward,1 who reported the case of a woman who developed an urticarial reaction and associated systemic symptoms following exposure to sunlight. By conducting some simple tests, he found that the reaction in this patient was triggered by exposure to UVA radiation and that other physical stimuli such as cold, heat, and X rays did not reproduce the reaction. The name solar urticaria was coined by Duke2 in 1923, when he described another case and compared solar urticaria to urticarial reactions precipitated by other physical stimuli. Since those early reports, many cases of solar urticaria have been described and a large body of literature on its photobiologic aspects has been published. A few studies have been made of the possible immunologic features of the disease and the results suggest that, in some cases, the pathogenesis may involve an interaction between nonionizing radiation and the immune system.

Keywords

Cellulose Fractionation Flare Histamine Prostaglandin 

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References

  1. 1.
    Ward SB: Erythema and urticaria with a condition resembling angioneurotic edema caused only by exposure to the sun’s rays. Med J 81:742–743, 1905.Google Scholar
  2. 2.
    Duke WW: Urticaria caused by light. JAMA 80:1835–1838, 1923.Google Scholar
  3. 3.
    Crow KD, Alexander E, Buck WHL, et al: Photosensitivity due to pitch. Br J Dermatol 73:220–232, 1961.PubMedCrossRefGoogle Scholar
  4. 4.
    Magnus IA, Jarrett A, Prankerd TAJ, et al: Erythropoietic protoporphyria: A new porphyria syndrome with solar urticaria due to protoporphyrinaemia. Lancet ii:448–451, 1961.CrossRefGoogle Scholar
  5. 5.
    Delorme P, Giroux JM: Solar urticaria as the presenting manifestation of systemic lupus erythematosus. Can Med Assoc J 95:539–542, 1966.PubMedGoogle Scholar
  6. 6.
    Williams DI: Systemic lupus erythematosus. J R Soc Med 60:299, 1967.Google Scholar
  7. 7.
    Frain-Bell W, Magnus IA: A study of the photosensitivity factor in cutaneous lymphocytoma. Br J Dermatol 84:25–31, 1971.PubMedCrossRefGoogle Scholar
  8. 8.
    Rubin L, Beal PI, Rothman S: A method for protection of patients with solar urticaria. J Invest Dermatol 8:189, 1947.PubMedGoogle Scholar
  9. 9.
    Ramsay CA: Solar urticaria treatment by inducing tolerance to artificial radiation and natural light. Arch Dermatol 113:1222–1225, 1977.PubMedCrossRefGoogle Scholar
  10. 10.
    Hawk JLM, Eady RAJ, Challoner AVJ, et al: Elevated blood histamine levels and mast cell degranulation in solar urticaria. Br J Clin Pharmacol 9:183–186, 1980.PubMedGoogle Scholar
  11. 11.
    Ramsay CA, Scrimenti RJ, Cripps DJ: Ultraviolet and visible action spectrum in a case of solar urticaria. Arch Dermatol 101:520–523, 1970.PubMedCrossRefGoogle Scholar
  12. 12.
    Holzle E, Hofmann C, Plewig G: PUVA-treatment for solar urticaria and persistent light reaction. Arch Dermatol Res 269:87–91, 1980.PubMedCrossRefGoogle Scholar
  13. 13.
    Keahey TM, Lavker RM, Kaidbey KH: Solar urticaria: Induction of tolerance and demonstration of a photoreactive serum factor. J Invest Dermatol 76:322, 1981.Google Scholar
  14. 14.
    Brunsting LA, Epstein JH: Solar urticaria. Dermatologica 115:171–180, 1957.PubMedCrossRefGoogle Scholar
  15. 15.
    Epstein JH, Vandenberg JJ, Wright WL: Solar urticaria. Arch Dermatol 88:135–141, 1963.PubMedGoogle Scholar
  16. 16.
    Willis I, Epstein JH: Solar- vs heat-induced urticaria. Arch Dermatol 110:389–392, 1974.PubMedCrossRefGoogle Scholar
  17. 17.
    Sams WM, Epstein JH, Winkelmann RK: Solar urticaria: Investigation of pathogenetic mechanisms. Arch Dermatol 99:390–397, 1969.PubMedCrossRefGoogle Scholar
  18. 18.
    De La Faille HB, Rottier PB, De La Faille-Kuyper EHB: Solar urticaria: A case with possible increase of skin mast cells. Br J Dermatol 92:101–107, 1975.CrossRefGoogle Scholar
  19. 19.
    Michell P, Hawk JLM, Shafrir A, et al: Assessing the treatment of solar urticaria: The dose-response as a quantifying approach. Dermatologica 160:198–207, 1980.PubMedCrossRefGoogle Scholar
  20. 20.
    Kobza A, Ramsay CA, Magnus IA: Oral β-carotene therapy in actinic reticuloid and solar urticaria. Br J Derm 88:157–166, 1973.CrossRefGoogle Scholar
  21. 21.
    Watkins AL: Infra-red urticaria. Arch Phys Ther 24:291–294, 1943.Google Scholar
  22. 22.
    Weber G: Urticaria-like reaction after x-ray treatment. J Invest Dermatol 30:311–313, 1958.PubMedGoogle Scholar
  23. 23.
    Ive H, Lloyd J, Magnus IA: Action spectra in idiopathic solar urticaria. Br J Dermatol 77:229–243, 1965.PubMedCrossRefGoogle Scholar
  24. 24.
    Harber LC, Holloway RM, Wheatley VR, et al: Immunologic and biophysical studies in solar urticaria. J Invest Dermatol 41:439–443, 1963.PubMedCrossRefGoogle Scholar
  25. 25.
    Harber LC, Baer RL: Classification and characteristics of photoallergy, in Urbach F (ed): Biologic Effects of UV Radiation. Oxford, Pergamon Press, 1969, 519.Google Scholar
  26. 26.
    Ravits M, Armstrong RB, Harber LC: Solar urticaria: Clinical features and wavelength dependence. Arch Dermatol 118:228–231, 1982.PubMedCrossRefGoogle Scholar
  27. 27.
    Horio T, Minami K: Solar urticaria: Photoallergen in a patient’s serum. Arch Dermatol 113:157–160, 1977.PubMedCrossRefGoogle Scholar
  28. 28.
    Horio T: Photoallergic urticaria induced by visible light. Arch Dermatol 114:1761–1764, 1978.PubMedCrossRefGoogle Scholar
  29. 29.
    Sams WM: Solar urticaria: Studies of the active serum factor. J Allergy 45:295–301, 1970.PubMedCrossRefGoogle Scholar
  30. 30.
    Sulzberger MB, Baer RL: Studies in hypersensitivity to light. J Invest Dermatol 6:345–348, 1945.PubMedCrossRefGoogle Scholar
  31. 31.
    Beal PL: Studies in solar urticaria. J Invest Dermatol 11:415–433, 1948.PubMedGoogle Scholar
  32. 32.
    Rantanen T, Suhonen R: Solar urticaria: A case with increased skin mast cell and good therapeutic response to an antihistamine. A eta Derm Venereol 60:363–365, 1980.Google Scholar
  33. 33.
    Soter NA, Waserman SI, Pathak MA, et al: Solar urticaria: Release of mast cell mediators into the circulation after experimental challenge. J Invest Dermatol 72:282, 1979 (abstr).Google Scholar
  34. 34.
    Hecke EV: Solar urticaria. Arch Dermatol 115:759, 1979.PubMedCrossRefGoogle Scholar

Copyright information

© Plenum Publishing Corporation 1983

Authors and Affiliations

  • Warwick L. Morison
    • 1
  1. 1.Basic Research Program-LBIFrederick Cancer Research FacilityFrederickUSA

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