Modified Fibers from Regenerated Collagen

  • James M. Brennan
  • Ferdinand Rodriguez
Part of the Polymer Science and Technology book series (volume 17)

Abstract

In a previous study, fibers were made from acid-soluble collagen coagulated in ammonium hydroxide solutions and cross-linked by glutaraldehyde1. The work is now extended to collagen modified by the addition of small amounts of methyl cellulose. Such fibers might be suitable as absorable sutures if the physical properties can be enhanced to a level competitive with silk and catgut2,3,.

Keywords

Cellulose Acetone Chromated Tyrosine Aldehyde 

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. 1.
    W. C. Schimpf, F. Rodriguez, I&EC Pdt. Res. Dev., 16, 90 (1977).CrossRefGoogle Scholar
  2. 2.
    A. L. Rubin., K. H. Stenzel, MIT Technol. Rev., 71 (2), 3 (Dec., 1968 ).Google Scholar
  3. 3.
    M. Chvapil, R. La Kronenthal, W. van Winkle, Jr., Int. Rev. Connect. Tissue Res., 6, 1 (1973).Google Scholar
  4. 4.
    A. L. Rubin, K. H. Stenzel, in “Biomaterials,” Plenum, New York, 1969.Google Scholar
  5. 5.
    A. G. Walton, J. Blackwell, “Biopolymers,” Academic Press, New York, 1973.Google Scholar
  6. 6.
    E. A. Balaz (Ed), “Chemistry and Molecular Biology of the Intracellular Matrix, Vol. 1,” Academic Press, New York, 1971.Google Scholar
  7. 7.
    A. L. Rubin, K. H. Stenzel, Biochemistry, 4, l8l (1965).CrossRefGoogle Scholar
  8. 8.
    F. O. Schmitt, et. al., Proc. Nat’l. Acad. Sci. U.S., 51, 493 (1964)Google Scholar
  9. 9.
    J. B. Hermann, Archives of Surgery, 106, 710 (1973).Google Scholar
  10. 10.
    F. A. Bovey, “The Effects of Ionizing Radiation on Natural and Synthetic High Polymers,” Interscience, New York, 1958.Google Scholar
  11. 11.
    A. Chapiro, “Radiation Chemistry of Polymer Systems,” Interscience, New York, 1962.Google Scholar
  12. 12.
    Go Hamed, F. Rodriguez, J. Appl. Polym. Sci., 19, 3299 (1975).CrossRefGoogle Scholar
  13. 13.
    C. W. Cater, J. Soc. Leather Trades ’ Chemists, 14, 259 (1963).Google Scholar
  14. 14.
    T. Miyata, T. Sohde, A. L. Rubin, K. H. Stenzel, Biochem. Biophys. Acta, 229, 672 (1971).Google Scholar
  15. 15.
    F. M. Richards, J. R. Knowles, J. Mol. Biol., 37, 321 (1968).Google Scholar
  16. 16.
    A. Veis in “Treatise on Collagen, Vol. 1,” (G. N. Ramachandran, Ed.), Academic Press, New York, 1967, chpt. 80Google Scholar
  17. 17.
    A. B. Savage in “Encycl. Polym. Sei. Tech., Vol. 3,” Wiley- Interscience, New York, 1967, pp. 472, 492.Google Scholar
  18. 18.
    L. Rebenfeld in “Encycl. Polym. Sci. Tech., Vol. 6,” Wiley- Interscience, New York, 1967, p. 505.Google Scholar
  19. 19.
    S. M. Atlas, H. F. Mark, E. Cernia (Eds.), “Man-Made Fibers, Vol. 1,” Wiley, New York, 1967, pp. 95–130.Google Scholar
  20. 20.
    J. M. Preston, “Fiber Science,” Textile Institute, Manchester, England, 1949, pp. 51–68.Google Scholar

Copyright information

© Plenum Press, New York 1983

Authors and Affiliations

  • James M. Brennan
    • 1
  • Ferdinand Rodriguez
    • 1
  1. 1.School of Chemical Engineering, Olin HallCornell UniversityIthacaUSA

Personalised recommendations