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Mutagenicity of Selected Chemicals in Drosophila

  • Chapter
Comparative Chemical Mutagenesis

Abstract

This review of mutagenicity data involving the 20 reference mutagens in Drosophila is restricted to data that were considered relevant for the purpose of the comparative evaluation. Although an effort was made to include information from as many sources as possible (approximately 500 papers were checked and representative material from about 140 papers was selected), the reports are not intended to review all studies reported in the literature Each of the 20 compounds is reviewed separately in a small report containing three sections (treatment conditions; biological effects; evaluation). References are given in a single bibliography at the end. In the following section we will consider briefly the genetic endpoints which were preferentially used for assaying the chemicals under consideration.

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Authors and Affiliations

  1. Department of Radiation Genetics and Chemical Mutagenesis, State University of Leiden, Leiden, The Netherlands

    E. Vogel & A. Schalet

  2. Department of Zoology and Physiology, Louisiana State University, Baton Rouge, Louisiana, USA

    W. R. Lee

  3. Institute für Toxikologie der ETH und der Universität Zürich, Schwerzenbach bei Zürich, Switzerland

    F. Würgler

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  1. E. Vogel
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  2. A. Schalet
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  3. W. R. Lee
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  4. F. Würgler
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Editors and Affiliations

  1. National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina, USA

    Frederick J. De Serres  & Michael D. Shelby  & 

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Vogel, E., Schalet, A., Lee, W.R., Würgler, F. (1981). Mutagenicity of Selected Chemicals in Drosophila. In: De Serres, F.J., Shelby, M.D. (eds) Comparative Chemical Mutagenesis. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-3409-5_9

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