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Comparative Mutagenicity of Epichlorohydrin and Cadmium

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Comparative Chemical Mutagenesis

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Abstract

Epichlorohydrin, \(\overline {O - C{H_2} - C} H - C{H_2}Cl\), is an important industrial chemical used in the production of many chemical compounds and polymers. Commercial U.S. production of epichlorohydrin was 550 million pounds in 1975, a 70% increase over the amounts produced in 1969. Its major uses are in the manufacture of glycerol and epoxy resins; other products in which it plays a role include emulsifiers, lubricants, dyestuffs, surfactants, and adhesives.

With the collaboration of B. Gledhill, T. Kada, A. Leonard, M. F. Lyon, V. Mayer, G. Newell, R. A. Nilan, G. Obe, I. F. Purchase and F. Zimmerman.

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References

  1. Rosenkranz, H. Personal communication.

    Google Scholar 

  2. Kada, T. Personal communication.

    Google Scholar 

  3. Elmore, J. D., Wong, J. L., Laumbach, A. D., and Streips, U. N. Biochem. Biophys. Acta 442: 405–419 (1976).

    Google Scholar 

  4. Strauss, B., and Okubo, S. J. Bacteriol. 79: 464–473 (1960).

    Google Scholar 

  5. Sram, R. J., Cerna, M., and Kucerová, M. Biol. Zentralbl. 95: 451–462 (1976).

    Google Scholar 

  6. Mukai, F. H., and Hawryluk, I. Mutat. Res. 21: 228 (1973).

    Google Scholar 

  7. Simmon, V. Personal communication.

    Google Scholar 

  8. Bridges, B. A. Unpublished data.

    Google Scholar 

  9. Voogd, C. E. Mutat. Res. 21: 52–53 (1973).

    Article  Google Scholar 

  10. Baranowska, H., Prazmo, W., and Putrament, A. Acta Microbiol. Pol. A7: 25–32 (1975).

    Google Scholar 

  11. Koelmark, G., and Giles, N. H. Genetics 40: 890–902 (1955).

    Google Scholar 

  12. Lundqvist, U., von Wettstein-Knowles, P., and von Wettstein, D. Hereditas 59. 473–504 (1968).

    Article  Google Scholar 

  13. Loveless, A. Nature 167: 338–342 (1951).

    Article  ADS  Google Scholar 

  14. Rapoport, I. A. Dokl. Akad. Nauk SSR 60: 469–472 (1948).

    Google Scholar 

  15. Knaap, A. Personal communication.

    Google Scholar 

  16. Kucerová, M., Polivkova, Z., Sram, R., and Matousek, V. Mutat. Res. 34: 271–278 (1976).

    Article  Google Scholar 

  17. Kucerovâ, M., and Polivkova, Z. Mutat. Res. 34: 279–290 (1976).

    Article  Google Scholar 

  18. Inui, N., and Kada, T. Personal communication.

    Google Scholar 

  19. Inui, N., Kaketoni, M., and Nishi, Y. Mutat. Res. 41: 351–360 (1976).

    Article  Google Scholar 

  20. Epstein, S. S., Arnold, E., Andrea, J., Bass, W., and Bishop, Y. Toxicol. Appl. Pharmacol. 23: 288–325 (1972).

    Article  Google Scholar 

  21. Kucerová, M., Zhurkov, V. S., Polivkova, Z., and Ivanova, J. E. Mutat. Res. 48: 355–360 (1977).

    Article  Google Scholar 

  22. Hahn, J. d. Nature 226: 87 (1970).

    Article  ADS  Google Scholar 

  23. Cooper, E. R. A., Jones, A. R., and Jackson, H. J. Reprod. Fertil. 38: 379–386 (1974).

    Article  Google Scholar 

  24. Jones, A. R., Davies, P., Edwards, K., and Jackson, H. Nature 224: 83 (1969).

    Article  ADS  Google Scholar 

  25. Kilham, D. J. Criteria for a Recommended Standard for Occupational Exposure to Epichlorhydrin. NIOSH, U.S. Department of Health, Education and Welfare, 1976.

    Google Scholar 

  26. Nishkioka, H. Mutat. Res. 26: 437–438 (1974).

    Google Scholar 

  27. Venitt, S., and Levy, L. S. Nature 250: 493–495 (1974).

    Article  ADS  Google Scholar 

  28. Parry, J. Personal communication.

    Google Scholar 

  29. Sörsa, M., and Pfeifer, S. Hereditas 74: 273–277 (1973).

    Google Scholar 

  30. Friberg, L., Piscator, M., Nordberg, G. F., and Kjellstroem, T. In: Cadmium in the Environment, CRC Press, Cleveland, Ohio, 1974, pp. 131–135.

    Google Scholar 

  31. Von Rosen, G. Hereditas 40: 258–263 (1954).

    Google Scholar 

  32. Degraeve, N. Rev. Cytol., Biol. Veg. 31: 233–244 (1971).

    Google Scholar 

  33. Von Rosen, G. Hereditas 43: 644–664 (1957).

    Article  Google Scholar 

  34. Ruposhev, A. R. Genetika 12 (3): 37–43 (1976).

    Google Scholar 

  35. Ruposhev, A. R. L. Tsitol. Genet. 10: 111–113 (1976).

    Google Scholar 

  36. Gläss, E. Z. Botanik 43: 359 (1955).

    Google Scholar 

  37. Gläss, E. Z. Botanik 44: 1–58 (1956).

    Google Scholar 

  38. Gläss, E. Chromosoma 8: 260–284 (1956).

    Article  Google Scholar 

  39. Anikeeva, I. D., Valuina, E. N., and Kogan, J. g. Genetika 11 (12): 78–83 (1975).

    Google Scholar 

  40. Roehr, G., and Bauchinger, M. Mutat. Res. 40: 124–130 (1976).

    Google Scholar 

  41. Shiraishi, Y., Kurahashi, H., and Yosida, T. H. Proc. Japan. Acad. 48: 133–137 (1972).

    Google Scholar 

  42. Deknudt, G. H., personal communication.

    Google Scholar 

  43. Zasukhina, G. D., Shalunova, N. V., Shvetsova, T. P., and Lomanova, G. A. Dokl. Biol Sci. 224: 425–427 (1975); Dokl. Akad Nauk SSSR 224: 1189–1191 (1975).

    Google Scholar 

  44. Gilliavod, N., and Léonard, A. Toxicology 5: 43–47 (1975).

    Article  Google Scholar 

  45. Suter, K. E. Mutat. Res. 30: 365–374 (1975).

    Article  Google Scholar 

  46. Dixon, R. L., Lee, I. P., and Sherins, R. J. Environ. Health Perspect. 13: 59–67 (1976).

    Article  MATH  Google Scholar 

  47. Shimada, T., Watanabe, T., and Endo, A. Mutat. Res. 40: 389–396 (1976).

    Article  Google Scholar 

  48. Léonard, A., Deknudt, G., and Debackere, M. Toxicology 2: 269–273 (1974).

    Article  Google Scholar 

  49. Doyle, J. J., Pfander, W. H., Crenshaw, D. B., and Shethen, J. M. Interface 31: 9 (1974).

    Google Scholar 

  50. Bauchinger, M., Schmid, E., Einbrcdt, H. J., and Dresp, J. Mutat. Res. 40: 57–62 (1976).

    Article  Google Scholar 

  51. Léonard, A., Deknudt, G., and Gilliavod, N. Ann. Gebloux 80 (2): 87–93 (1974).

    Google Scholar 

  52. Deknudt, G., and Leonard, A. Environ. Physiol. Biochem. 5: 319–327 (1975).

    Google Scholar 

  53. Deknudt, G., Léonard, A., and Ivanov, B. Environ. Physiol. Biochem. 3: 132–133 (1973).

    Google Scholar 

  54. Bui, T.-H., Lindsten, J., and Nordberg, G. F. Environ. Res. 9: 187–195 (1975).

    Article  Google Scholar 

  55. Shiraishi, Y. Humangenetik 27: 31–41 (1975).

    Google Scholar 

  56. Shiraishi, Y., and Yosida, T. H. Ann. Rept. Natl. Inst. Genetics 22: 44–45 (1971).

    Google Scholar 

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Author information

Authors and Affiliations

  1. MRC Cell Mutation Unit, University of Sussex, England

    B. A. Bridges

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  1. B. A. Bridges
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Editors and Affiliations

  1. National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina, USA

    Frederick J. De Serres  & Michael D. Shelby  & 

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© 1981 Plenum Press, New York

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Bridges, B.A. (1981). Comparative Mutagenicity of Epichlorohydrin and Cadmium. In: De Serres, F.J., Shelby, M.D. (eds) Comparative Chemical Mutagenesis. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-3409-5_35

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  • DOI: https://doi.org/10.1007/978-1-4613-3409-5_35

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4613-3411-8

  • Online ISBN: 978-1-4613-3409-5

  • eBook Packages: Springer Book Archive

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