Skip to main content

Excessive Nutrient Intakes

  • Chapter
Adverse Effects of Foods

Abstract

Food and drink are prepared and consumed as a matter of custom, to satisfy the pangs of hunger and thirst, and as one of the more delightful social activities of man. It is only as an afterthought that the ordinary person pays attention to the nutritional value of food and drink. For the masses in developing countries, knowing where tomorrow’s meal is to come from presents a constantly recurring problem. It is only in recent years that those who live in technologically developed societies have been made increasingly aware of the possible hazards to health of excessive consumption. Attention in this regard has mainly been directed toward the major energy sources, fats and carbohydrates, but consideration also needs to be given to some vitamins and elements.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 39.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 54.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  • Abrahamson, I. A., and Abrahamson, I. A., Jr., 1962, Hypercarotenemia, Arch. Ophthalmol. 68: 4.

    Google Scholar 

  • Adams, C. F., 1975, Nutritive value of American foods in common units, Agriculture Handbook No. 456, U.S. Department of Agriculture, Agricultural Research Service, Washington, D.C.

    Google Scholar 

  • Alfin-Slater, R. B., and Mirenda, R., 1980, Nutrient requirements: What they are and bases for recommendations, in: Human Nutrition a Comprehensive Treatise, Vol. 3A, Nutrition and the Adult: Macronutrients ( R. B. Alfin-Slater and D. Kritchevsky, eds.), pp. 1–48, Plenum, New York.

    Google Scholar 

  • Almond, S., and Logan, R. F. L., 1942, Carotinaemia, Br. Med. J. 2: 239.

    Article  CAS  Google Scholar 

  • American Academy of Pediatrics Committee on Nutrition, 1974, Salt intake and eating patterns of infants and children in relation to blood pressure, Pediatrics 53: 115.

    Google Scholar 

  • Bierman, E. L., 1979, Carbohydrates, sucrose, and human disease, Am. J. Clin. Nutr. 32: 2712.

    CAS  Google Scholar 

  • Black, J. A., and Bonham Carter, R. E., 1963, Association between aortic stenosis and facies of severe infantile hypercalcaemia, Lancet 2: 745.

    Article  CAS  Google Scholar 

  • Blitzer, P. H., Blitzer, E. C., and Rimm, A. A., 1976, Association between teen-obesity and cancer in 56,111 women. All cancers and endometrial carcinoma, Prev. Med. 5: 20.

    Article  CAS  Google Scholar 

  • Bondy, P. K., and Rosenberg, L. E., 1980, Metabolic Control and Disease, 8th ed., Saunders, Philadelphia.

    Google Scholar 

  • Bothwell, T. H., and Finch, C. A., 1962, Iron Metabolism, Little Brown, Boston.

    Google Scholar 

  • British Paediatric Association, 1964, Infant hypercalcaemia, nutritional rickets and infantile scurvy in Great Britain, Br. Med. J. 1: 1659.

    Article  Google Scholar 

  • Chanarin, I., 1969, The Megaloblastic Anaemias, Blackwell, Oxford.

    Google Scholar 

  • Cook, J. D., 1977, Absorption of food iron, Fed. Proc. Fed. Am. Soc. Exp. Biol. 36: 2028.

    CAS  Google Scholar 

  • Corrigan, J. J., Jr., and Marcus, F. I., 1974, Coagulopathy associated with vitamin E ingestion, J. Am. Med. Assoc. 220: 1300.

    Article  Google Scholar 

  • D’Alonzo, C. A., and Pell, S., 1968, Cardiovascular disease among problem drinkers, J. Med. 10: 344.

    Google Scholar 

  • Danforth, E., Jr., Desileto, E. S., Hortan, E. S., Sims, E. A. H., Burger, A. G., Braveman, L. E., Vagenakis, A. G., and Ingbar, S. H., 1975, Reciprocal changes in serum triiodothyronine (T3) and reverse triiodothyronine (rT3) induced by altering the carbohydrate content of the diet, Clin. Res. 23: 573A.

    Google Scholar 

  • DeWaard, F., and Baanders-van Halewun, E. A., 1969, Cross sectional data on estrogenic smears in a postmenopausal population, Acta Cytol. 13: 675.

    Google Scholar 

  • Dietschy, J. M., and Wilson, J. D., 1970a,b,c, Regulation of cholesterol metabolism, N. Engl. J. Med. 282: 1128, 1179, 1241.

    Article  CAS  Google Scholar 

  • Dobbs, R. J., and Baird, I. M., 1977, Effect of wholemeal and white bread on iron absorption in normal people, Br. Med. J. 1: 1641.

    Article  CAS  Google Scholar 

  • Farell, P. M., and Willison, J. W., 1975, Megavitamin E supplementation in man, Fed. Proc. Fed. Am. Soc. Exp. Biol. 34: 912.

    Google Scholar 

  • Finberg, L., Kiley, J., and Luttrell, C. N., 1963, Mass accidental salt poisoning in infancy: A study of a hospital disaster, J. Am. Med. Assoc. 184: 187.

    CAS  Google Scholar 

  • Fisher, E. R., and Tisherman, S., 1960, The association of idiopathic hemochromatosis and excessive iron overload. Report of a case with comment relative to the concept of exogenous hemochromatosis. Arch. Pathol. 69: 683.

    CAS  Google Scholar 

  • Food and Nutrition Board, 1980, Recommended Dietary Allowances, 9th rev. ed., National Academy of Sciences, National Research Council, Washington, D.C.

    Google Scholar 

  • Garrow, J. S., Blaza, S., Warwick, P., and Ashwell, M., 1980, Predisposition to obesity, Lancet 1: 1103.

    Article  CAS  Google Scholar 

  • Goodman, D. S., 1978, Diseases of lipid and lipoprotein metabolism, in: The Year in Metabolism 1977 ( N. Freinkel, ed.), pp. 183–218, Plenum, New York.

    Google Scholar 

  • Greaves, J. P., and Hollingsworth, D. F., 1966, Trends in food consumption in the United Kingdom, World Rev. Nutr. Diet. 6: 34.

    CAS  Google Scholar 

  • Grinvalsky, H. T., and Fitch, D. M., 1969, A distinctive cardiomyopathy occurring in Omaha, Nebraska: Pathological aspects, Ann N.Y. Acad. Sci. 156: 544.

    Article  CAS  Google Scholar 

  • Haghshenass, M., Mahlondji, M., Reinhold, J. G., and Mohammadi, N., 1972, Iron deficiency anemia in an Iranian population associated with high intakes of iron, Am. J. Clin. Nutr. 25: 1143.

    CAS  Google Scholar 

  • Himsworth, H. P., 1949, Diet in the etiology of human diabetes, Proc. R. Soc. Med. 42: 323.

    Google Scholar 

  • Hirsch, J., 1978, What’s new in the treatment of obesity? in: The Year in Metabolism 1977 ( N. Freinkel, ed.), pp. 169–182, Plenum, New York.

    Google Scholar 

  • Hoffman, R., Mann, J., Calderone, J., Trumbull, J., and Burkhart, M., 1980, Acute fluoride poisoning in a New Mexico elementary school, Pediatrics 65: 897.

    CAS  Google Scholar 

  • Jeghers, H., and Marrato, H., 1958, Hypervitaminosis A. Its broadening spectrum, Am. J. Clin. Nutr. 6: 335.

    CAS  Google Scholar 

  • Jensen, R. G., Hagerty, M. M., and MacMahon, K. E., 1978, Lipids of human milk and infant formulas: A review, Am. J. Clin. Nutr. 31: 990.

    CAS  Google Scholar 

  • Johnson, B. G., and Nilsson-Ehle, P., 1978, Alcohol consumption and high density lipoprotein, N. Engl. J. Med. 298: 633.

    Google Scholar 

  • Joint Working Party of the Royal College of Physicians of London and the British Cardiac Society, 1976, Prevention of coronary heart disease, J. R. Coll. Physicians London 10: 213.

    Google Scholar 

  • Kahn, H. A., Herman, J. B., Medalie, J. H., Neufeld, H. N., Riss, E., and Goldbourt, U., 1971, Factors related to diabetes incidence: A multivariate analysis of two years observations on 10,000 men, J. Chronic Dis. 23: 617.

    Article  CAS  Google Scholar 

  • Keys, A., 1971, Sucrose in the diet and coronary heart disease, Atherosclerosis 14: 193.

    Article  CAS  Google Scholar 

  • Klatsky, A. L., Friedman, C. D., and Siegelaut, A. B., 1974, Alcohol consumption before myocardial infarction. Results from the Kaiser-Permanente epidemiologic study of myocardial infarction, Ann. Intern. Med. 81: 294.

    CAS  Google Scholar 

  • Klatsky, A. L., Friedman, G. D., Siegelaut, A. B., and Gerard, M. D., 1977, Alcohol consumption and blood pressure. Kaiser-Permanente multiphasic health examination. N. Engl. J. Med. 296: 1194.

    Article  CAS  Google Scholar 

  • Krishnamachari, K. A. V. R., and Krishnaswamy, K., 1973, Genu valgum and osteoporosis in an area of endemic fluorosis, Lancet 2: 877.

    Article  CAS  Google Scholar 

  • Kritchevsky, D. and Czarnecki, S. K., 1980, Nutrients with special functions: Cholesterol, in: Human Nutrition: A Comprehensive Treatise, Vol. 3A Nutrition and the Adult: Macronutrients ( R. B. Alfin-Slater and D. Kritchevsky, eds.), pp. 239–258, Plenum, New York.

    Google Scholar 

  • Lakdawala, D. R., and Widdowson, E. M., 1977, Vitamin-D in human milk, Lancet 1: 167.

    Article  CAS  Google Scholar 

  • Leitner, Z. A., Moore, T., and Sharman, I. M., 1975, Fatal self-medication with retinol and carrot juice, Proc. Nutr. Soc. 34: 44A.

    CAS  Google Scholar 

  • Lelbach, W. K., 1975, Cirrhosis in the alcoholic and its relation to the volume of alcohol abuse, Ann. N.Y. Acad. Sci. 252: 85.

    Article  CAS  Google Scholar 

  • Lew, E. A., and Garfinkel, L., 1979, Variations in mortality by weight among 750,000 men and women, J. Chronic Dis. 32: 563.

    Article  CAS  Google Scholar 

  • Little, J. A., McGuire, V., and Derksen, A., 1979, Available carbohydrates, in: Nutrition, Lipids, and Coronary Heart Disease ( R. Levy, B. Rifkind, B. Dennis and N. Erust, eds.), pp. 119–148, Raven, New York.

    Google Scholar 

  • Lombaert, A., and Carton, J., 1976, Benign intracranial hypertension due to A hypervitaminosis in adults and adolescents: A review, Eur. Neurol. 14: 340.

    Article  CAS  Google Scholar 

  • Mahoney, C. P., Margolis, M. T., Knauss, T. A., and Labbe, R. F., 1980, Chronic vitamin A intoxication in infants fed chicken liver, Pediatrics 65: 893.

    CAS  Google Scholar 

  • Manios, S., Panagou, M., Tsakalidis, D., and Kovatsis, A., 1966, Hypercalcemie idiopathique chez des triplees. Arch. Fr. Pediatr. 23: 63.

    CAS  Google Scholar 

  • Marston, R., and Page, L., 1978, Nat. Food Rev. NFR-5: 28.

    Google Scholar 

  • Masironi, R., 1970, Dietary factors and coronary heart disease, Bull. W.H.O. 42: 103.

    CAS  Google Scholar 

  • McGill, H. C., Jr., 1979, Appraisal of cholesterol as a causative factor in atherogenesis, Am. J. Clin. Nutr. 32: 2632.

    CAS  Google Scholar 

  • McLaren, D. S., 1981, The luxis vitamins—A and B12, Am. J. Clin. Nutr. 34: 1161.

    Google Scholar 

  • Mead, J. F., 1980, Nutrients with special functions: Essential fatty acids, in: Human Nutrition a Comprehensive Treatise, Vol. 3A Nutrition and the Adult: Macronutrients ( R.B. Alfin-Slater and D. Kritchevsky, eds.), pp. 213–238, Plenum, New York.

    Google Scholar 

  • Mellette, S. J., and Leone, L. A., 1960, Influence of age, sex, strain of rat and fat soluble vitamins on hemorrhagic syndromes in rats fed irradiated beef, Fed. Proc. Fed. Am. Soc. Exp. Biol. 19: 1045.

    CAS  Google Scholar 

  • Mistuanaga, T., 1974, Some properties of protease inhibitors in wheat grain, J. Nutr. Sci. Vitaminol. 20: 153.

    Article  Google Scholar 

  • Moore, C. V., 1973, Iron, in: Modern Nutrition in Health and Disease, 5th ed. ( R. S. Goodhart and M. E. Shils, eds.), pp. 319–320, Lea and Febiger, Philadelphia.

    Google Scholar 

  • Moore, T., 1957, Vitamin A, pp. 442–455, Elsevier, London.

    Google Scholar 

  • Morris, J. N., Marr, J. W., and Clayton, D. G., 1977, Diet and heart: A postscript, Br. Med. J. 2: 1307.

    Article  CAS  Google Scholar 

  • Mosher, L. R., 1970, Nicotinic acid side effects and toxicity. A review, Am. J. Psychiatry 126: 1290.

    CAS  Google Scholar 

  • Myer, T. C., and Angus, J., 1956, The effect of large doses of “synavit” in the newborn, Arch. Dis. Child. 31: 212.

    Article  Google Scholar 

  • Neville, J. N., Eagles, E. A., Samson, G., and Olson, R. E., 1968, Nutritional status of alcoholics, Am. J. Clin. Nutr. 21: 1329.

    CAS  Google Scholar 

  • Reinhold, J. G., Nasr, K., Lahimgarzadeh, A., and Hedayati, H., 1973, Effects of purified phytate and phytate-rich bread upon metabolism of zinc, calcium phosphorus and nitrogen in man, Lancet 1: 28.

    Google Scholar 

  • Reinhold, J. G., Faradji, B., Abadi, P., and Ismail-Beigi, F., 1976, Decreased absorption of calcium, magnesium, zinc and phosphorus by humans due to increased fiber and phosphorus consumption as wheat bread. J. Nutr. 106: 493.

    CAS  Google Scholar 

  • Ries, W., 1973, Feeding behaviour in obesity, Proc. Nutr. Soc. 32: 187.

    Article  CAS  Google Scholar 

  • Robboy, M. S., Sato, A. S., and Schwabe, A. D., 1974, The hypercarotenemia in anorexia nervosa: A comparison of vitamin A and carotene levels in various forms of menstrual dysfunction and cachexia, Am. J. Clin. Nutr. 27: 362.

    CAS  Google Scholar 

  • Roe, D. A., 1966, Nutrient toxicity with excessive intake. II. Mineral overload, N.Y. State J. Med. 66: 1233.

    Google Scholar 

  • Russell, R. M., Boyer, J. L., and Bagheri, S. A., 1974, Hepatic injury from chronic hypervitaminosis A resulting in portal hypertension and ascites, N. Engl. J. Med. 291: 435.

    Article  CAS  Google Scholar 

  • St. Leger, A. S., Cochrane, A. L., and Moore, F., 1979, Factors associated with cardiac mortality in developed countries with particular reference to the consumption of wine, Lancet 1: 1017.

    Article  CAS  Google Scholar 

  • Scheinin, A., Makinen, K. K., and Ylitalo, K., 1975, Turku sugar studies. I. An intermediate report on the effect of sucrose, fructose and xylitol diets on the caries incidence of man, Acta Odontol. Scand. Suppl. 33 (70): 5.

    Google Scholar 

  • Schneeman, B. O., 1977, The effect of plant fiber on trypsin and chymotrypsin activity in vitro, Fed. Proc. Fed. Am. Soc. Exp. Biol. 36: 1118.

    Google Scholar 

  • Schrauzer, G. N., 1979, Vitamin C: Conservative human requirements and aspects of overdosage, in: International Review of Biochemistry, Biochemistry of Nutrition IA, Vol. 27 ( A. Neuberger and T. H. Jukes, eds.), pp. 168–188, University Park Press, Baltimore.

    Google Scholar 

  • Shaw, J. H., 1954, Fluoridation as a Public Health Measure, p. 127, American Association for the Advancement of Science, Washington, D.C.

    Google Scholar 

  • Sims, E. A. H., Danforth, E., Jr., Horton, E. S., Bray, G. A., Glennon, J. A., and Salaus, L. B., 1973, Endocrine and metabolic effects of experimental obesity in man, Recent Prog. Horm. Res. 29: 457.

    CAS  Google Scholar 

  • Singh, A., Jolly, S. S., Bansal, D. C., and Mathur, C. C., 1963, Endemic-fluorosis. Epidemiological, clinical, and biochemical study of chronic fluorine intoxication in Punjab, India, Medicine Baltimore 42: 229.

    CAS  Google Scholar 

  • Smith, W. L., Franken, E. A., Jr., Grossfeld, J. L., and Ballantine, T. V. N., 1977, Pneumatosis of the bowel secondary to acute iron poisoning, Radiology 122: 192.

    CAS  Google Scholar 

  • Society of Actuaries, 1959, Build and Blood Pressure Studies, 1957, Vol. 1, Society of Actuaries, Chicago.

    Google Scholar 

  • Stone, D. B., and Connor, W. E., 1963, The prolonged effects of a low cholesterol, high carbohydrate diet upon the serum lipids in diabetic patients, Diabetes 12: 127.

    CAS  Google Scholar 

  • Sutcliffe, M. M. L., 1968, Volvulus of the sigmoid colon, Br. J. Surg. 55: 903.

    Article  CAS  Google Scholar 

  • Tobian, L., Jr., 1979, Sodium: Dietary salt (sodium) and hypertension, Am. J. Clin. Nutr. 32: 2659, 2739.

    CAS  Google Scholar 

  • Van Itallie, T. B., 1979, Obesity: Adverse effects on health and longevity, Am. J. Clin. Nutr. 32: 2723.

    Google Scholar 

  • Vilter, R. W., Horrigan, D., Mueller, J. F., Jarrold, T., Vilter, C. F., Hawkins, V., and Seaman, A., 1950, Studies on the relationships of vitamin B12, folic acid, thymine, uracil, and methyl group donors in persons with pernicious anemia and related megaloblastic anemias, Blood 5: 495.

    Google Scholar 

  • West, K. M., 1978, Epidemiology of Diabetes and its Vascular Lesions, pp. 224–274, Elsevier, New York.

    Google Scholar 

  • Williamson, R., 1980, Diet and bowel cancer, Br. Med. J. 2: 146.

    Article  Google Scholar 

  • Yano, K., Rhoads, G. G., and Kagan, A., 1977, Coffee, alcohol and risk of coronary heart disease among Japanese men living in Hawaii, N. Engl. J. Med. 297: 405.

    Article  CAS  Google Scholar 

  • Yudkin, J., 1957, Diet and coronary thrombosis: Hypothesis and fact, Lancet 2: 155.

    Article  Google Scholar 

  • Yudkin, J., 1964, Dietary fat and dietary sugar in relation to ischaemic heart disease, Lancet 2: 4.

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 1982 Plenum Press, New York

About this chapter

Cite this chapter

McLaren, D.S. (1982). Excessive Nutrient Intakes. In: Jelliffe, E.F.P., Jelliffe, D.B. (eds) Adverse Effects of Foods. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-3359-3_32

Download citation

  • DOI: https://doi.org/10.1007/978-1-4613-3359-3_32

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4613-3361-6

  • Online ISBN: 978-1-4613-3359-3

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics