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Adverse Effects of Foods in Genetic Disorders

  • Meinhard Robinow

Abstract

Most products of food metabolism have adverse effects on health if their concentrations in blood and extra- and intracellular fluids exceed narrow physiologic limits. Homeostasis, the maintenance of normal concentrations, is achieved by a vast number of genetically determined enzymatic processes that regulate digestion, absorption, transport, intermediate metabolism, and excretion.

Keywords

Celiac Disease Glycogen Storage Disease G6PD Deficiency Wilson Disease Lactase Deficiency 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. Ament, M. E., Perera, D. D., and Esther, L. J., 1973, Sucrase-isomaltase deficiency—a frequently misdiagnosed disease, J. Pediat. 83: 721–727.CrossRefGoogle Scholar
  2. Ament, M. E., 1979, Celiac Sprue in: Nelson, Textbook of Pediatrics, 11th ed. (V. Vaughn, J. McCay, and R. E. Behrman, eds.), p. 1083, W. B. Saunders, Philadelphia.Google Scholar
  3. Barry, R. E., and Read, A. E., 1973, Celiac disease and malignancy, Q. J. Med. 42: 665–675.Google Scholar
  4. Bayless, T. M., and Rosenzweig, N. S., 1966, A racial difference in incidence of lactase deficiency. J. Am. Med. Assoc. 197: 968–972.CrossRefGoogle Scholar
  5. Beutler, E., Baluda, M. C., Sturgeon, P., and Day, R. W., 1965, A new genetic abnormality resulting in galactose-1-phosphate uridyl transferase deficiency, Lancet 1: 353.CrossRefGoogle Scholar
  6. Beutler, E., 1970, L-dopa and favism, Blood 36: 523–525.Google Scholar
  7. Blackwell, B., 1963, Hypertensive crisis due to monoamine oxidase inhibitors, Lancet 2: 849.CrossRefGoogle Scholar
  8. Bottini, E. Lucarelli, P., Agostino, R., Palmarino, R., Businco, L., and Antagnoni, G., 1971, Favism: Association with erythrocyte acid phosphatase phenotype, Science 171: 409–411.CrossRefGoogle Scholar
  9. Danks, D. M., Cotton, R. G. H., and Schlesinger, P., 1979, Diagnosis of malignant hyperphenylalanemia, Arch. Dis. Child. 54: 329.CrossRefGoogle Scholar
  10. David, T. J., and Adjukiewicz, 1975, A family study of celiac disease, J. Med. Genet. 12: 79–82.CrossRefGoogle Scholar
  11. Falchuk, Z. M., Rogentine, G. M., and Strober, W., 1972, Predominance of histocompatibility antigen HL-A 8 in patients with gluten sensitive enteropathy, J. Clin. Invest. 51: 1602–1605.CrossRefGoogle Scholar
  12. Feingold, B. F., 1975, Hyperkinesis and learning disabilities linked to artificial food flavors and colors, Am. J. Nurs. 75: 797–803.Google Scholar
  13. Froesch, E. R., Wolf, H. P., Baitsch, H. H., Prader, A., and Labhart, A., 1963, Hereditary fructose intolerance: An inborn error of fructose metabolism, Am. J. Med. 34: 151.CrossRefGoogle Scholar
  14. Gray, G. M., 1978, Intestinal disaccharidase deficiencies and glucose-galactose malabsorption, in: The Metabolic Basis of Inherited Disease, 4th ed. ( J. B. Stanbury, J. B. Wyngaarden, and D. S. Frederickson, eds.), pp. 1526–1536, McGraw-Hill, New York.Google Scholar
  15. Hannington, E., 1967, Preliminary report of tyramine headache, Br. Med. J. 2: 250.CrossRefGoogle Scholar
  16. Henderson, W. R., and Raskin, N. H., 1972, “Hot dog” headache: Individual susceptibility to nitrate, Lancet 2:250.Google Scholar
  17. Holzel, A., Mereu, T., and Thomson, M. L., 1962, Severe lactose intolerance in infancy, Lancet 2: 1346.CrossRefGoogle Scholar
  18. Kattamis, A., Kyriazakou, M., and Chaidas, S., 1969, Favism, clinical and biochemical data, J. Med. Genet. 6: 34–41.CrossRefGoogle Scholar
  19. Kellermann, G., Luyten-Kellermann, M., and Shaw, C. R., 1973a, Genetic variation of aryl hydrocarbon hydroxylase in human lumphocytes, Am. J. Hum. Genet. 25: 327–331.Google Scholar
  20. Kellermann, G., Shaw, C. R., and Luyten-Kellermann, M., 1973b, Aryl hydrocarbon hydroxylase inductibility and bronchogenic carcinoma, N. Engl. J. Med. 289: 934–937.CrossRefGoogle Scholar
  21. La Du, B. N., 1978, Histidinemia, in: The Metabolic Basis of Inherited Disease, 4th ed. ( J. B. Stanbury, J. B. J. Wyngaarden, and D. S. Frederickson, eds.), pp. 317–327, McGraw-Hill, New York.Google Scholar
  22. Lindquist, B., Meuwisse, G. W., Melin, K., 1962, Glucose-galactose malabsorption, Lancet 2: 666.CrossRefGoogle Scholar
  23. Longdon, P. J., and Forsythe, W. I., 1979, Migraine in childhood. A review, Clin. Pediatr. 18: 353–356.CrossRefGoogle Scholar
  24. Mager, J., Glaser, G., Razin, A., Isak, C., Bien, S., and Noam, M., 1965, Metabolic effects of pyrimidines derived from glycosides on human erythrocytes deficient in glucose-6-phosphate dehydrogenase, Biochem. Biophys. Res. Comm. 20: 235–240.CrossRefGoogle Scholar
  25. McKusick, V. A., 1978, Mendelian Inheritance in Man, 5th ed., Johns Hopkins University Press, Baltimore, Maryland.Google Scholar
  26. Mentzler, W. C., and Collier, E., 1975, Hydrops fetalis associated with G-6-PD deficiency and maternal ingestion of fava beans and ascorbic acid, J. Pediatr. 86: 565–567.CrossRefGoogle Scholar
  27. Motulsky, A. G., 1964, Hereditary red cell traits and malaria, Am. J. Trop. Med. 13: 147–155.Google Scholar
  28. Paigen, B., Gurtoo, H. L., Minowada, J., Houten, L., Vincent, R., Paigen, K., Parker, N. E., Ward, E., and Hayner, N. T., 1977, Questionable relation of aryl hydrocarbon hydroxylase to lung cancer, N. Engl. J. Med. 297: 346–350.CrossRefGoogle Scholar
  29. Pollycove, M., 1978, Hemochromatosis, in: The Metabolic Basis of Inherited Disease, 4th ed. ( J. B. Stanbury, J. B. Wyngaarden, and D. S. Frederickson, eds.), pp. 1127–1164, McGraw-Hill, New York.Google Scholar
  30. Sandler, M., Yondim, M. B., and Harrington, E., 1974, A phenylethylamine oxidizing defect in migraine, Nature 250: 337–339.CrossRefGoogle Scholar
  31. Sansone, G., Piga, A. M., and Segni, G., 1958, El Favismo, Minerva Med., Torino, Italy.Google Scholar
  32. Sass-Kortsak, A. and Beam, A., 1978, Hereditary disorders of copper metabolism, in: The Metabolic Basis of Inherited Disease, 4th ed. ( J. B. Stanbury, J. B. Wyngaarden, and D. S. Frederickson, eds.), pp. 1098–1126, McGraw-Hill, New York.Google Scholar
  33. Segal, S., 1978, Disorders of galactose metabolism, in: The Metabolic Basis of Inherited Disease, 4th ed. ( J. B. Stanbury, J. B. Wyngaarden, and D. S. Frederickson, eds.), pp. 160–181, McGraw- Hill, New York.Google Scholar
  34. Schaumberg, H. H., Byck, R., Gerstl, R., and Mashman, J. H., 1969, Monosodium 1-glutamate: Its pharmacology and role in the Chinese Restaurant syndrome, Science 163: 826–828.CrossRefGoogle Scholar
  35. Smith, I., Clayton, B. E., and Wolff, O. H., 1975, new variant of phenylketonuria with progressive neurologic illness, Lancet 1: 1108–1111.Google Scholar
  36. Stammatoyannopoulis, G., Fraser, G. R., Motulsky, A. G., Fessas, P., Akrirakisn, A., and Papayannapoulou, T., 1966, On the familial predisposition of favism, Am. J. Hum Genet. 18: 253–263.Google Scholar
  37. Stanbury, J. B., Wyngaarden, J. B., and Frederickson, D. S. (eds.), 1978, The Metabolic Basis of Inherited Disease, 4th edition, McGraw-Hill, New York.Google Scholar
  38. Sunshine, P., and Kretschmer, N., 1964, Studies of small intestine during development III. Infantile diarrhea associated with intolerance to disaccharides, Pediatrics 34: 38–50.Google Scholar
  39. Szeinberg, A., Sheba, C., Hirshorn, N., and Bodonyi, E., 1957, Studies on erythrocytes in cases with past history of favism and drug induced hemolytic anemia, Blood 12: 603–616.Google Scholar
  40. Tarlov, A. R., Brewer, G. J., Carson, P. E., and Alving, A. S., 1962, Primaquine sensitivity. Glucose-6-Phosphate dehydrogenase deficiency and biological significance, Arch. Int. Med. 109: 209–234.Google Scholar
  41. Tourian, A. Y., and Sidbury, J. B., 1978, Phenylketonuria, in: The Metabolic Basis of Inherited Disease, 4th ed. ( J. B. Stanbury, J. B. Wyngaarden, and D. S. Frederickson, eds.), pp. 240–255, McGraw-Hill, New York.Google Scholar
  42. Wynder, E. L., 1979, Dietary habits and cancer epidemiology, Cancer 43: 1955–1961.CrossRefGoogle Scholar
  43. Wynder, E. L., 1980, Dietary factors related to breast cancer, Cancer 46: 899–904.CrossRefGoogle Scholar

Copyright information

© Plenum Press, New York 1982

Authors and Affiliations

  • Meinhard Robinow
    • 1
  1. 1.Department of Pediatrics, School of MedicineWright State UniversityDaytonUSA

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