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Evolution of Mitochondrial Studies

  • Chapter
Mitochondria

Part of the book series: Cellular Organelles ((BLSC))

Abstract

The notion of the compartmentalization of cellular functions, often by means of different organelles, arose from the convergence of two independent lines of investigation, one concentrating on cytological observations of cell inclusions and the other on biochemical studies of various metabolic pathways. The convergence occurred during the period of 1940–1960 when many important technical advances were made in the fractionation and isolation of reasonably homogeneous subcellular components. This meant that it became possible in many instances to assign specific functions to particular organelles or compartments of the cell. Today, every student of biology is aware of the fact that the mitochondrion is a specialized organelle whose primary functions are the conservation of oxidatively derived energy and its utilization for ATP synthesis. Some of the earlier developments that led to this recognition and other more recent highlights of studies of mitochondrial structure and function will be traced briefly in this chapter.

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Authors and Affiliations

  1. Columbia University, New York, New York, USA

    Alexander Tzagoloff

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  1. Alexander Tzagoloff
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© 1982 Plenum Press, New York

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Tzagoloff, A. (1982). Evolution of Mitochondrial Studies. In: Mitochondria. Cellular Organelles. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-3294-7_1

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  • DOI: https://doi.org/10.1007/978-1-4613-3294-7_1

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4613-3296-1

  • Online ISBN: 978-1-4613-3294-7

  • eBook Packages: Springer Book Archive

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