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Taurine Biosynthesis in Ox Retina

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Book cover Natural Sulfur Compounds

Abstract

Taurine is present in high concentrations in the retina (1–7) where it constitutes 40–50% of the total aminoacid pool (4, 6).

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References

  1. R.Kubicek,and A,Dolenek, Taurine et acides aminés dans la rétine des animauxf J,Chromatogr. f 1:266 (1958).

    Google Scholar 

  2. J. Brotherton, Studies on the metabolism of the rat retina with special reference to retinitis pigmentosa. II. Amino acid content as shown by chromatography. Ex. Eve Res.. 1: 246 (1962).

    Article  CAS  Google Scholar 

  3. A.I.Cohen, M.McDaniel, and H.T.Orr, Absolute levels of some free amino acids in normal and biologically fractionated retinas, Invest. Ophtalmol., 12: 686 (1973).

    Google Scholar 

  4. S.Macaione, P. Ruggeri, F. De luca,and G. Tucci, Free amino acids in developing rat retinaT J, Neurochem. 7 22: 887 (1974).

    Google Scholar 

  5. H.T.Orr, A. I.Cohen,and J. A.Carter, The levels of free taurine, glutamate, glycine and amino butyrric acid during the postnatal development of the normal and dystrophic retina of the mouse, Exp. Eye Res.. 23: 377 (1976).

    Google Scholar 

  6. H.Pasantes-Morales, J.Klethi,M.Ledig,and P.MandeL Free amino acids of chicken and rat retina, Brain Res. T 41: 494 (1972).

    Google Scholar 

  7. K. Yamamoto, Y. Yoshitani, H. Fuji ware,and K.Matsuura, Study on free amino acids in the retina, Acta Soc.Ophtalmol. Jpn., 74: 1561 (1970).

    CAS  Google Scholar 

  8. H. T.Orr, A. I. Cohen,and O. H.Lowry, The distribution of taurine in the vertebrate retina. J. Neurochem. r 26: 609 (1976).

    Google Scholar 

  9. A. J. Kennedy,and M. J. Voaden, Free amino acids in the photoreceptor eel I s of the frog retina, J. Neurochem,, 23: 1 093 (1974).

    Google Scholar 

  10. P.Keen and R. A. Yates, Distribution of amino acids in subdivided rat retinae, Br, J.Pharmacol-, 52: 1 18 (1974).

    Google Scholar 

  11. K. E. Rasmussen, A morphometric study of the Müller cell cytoplasm in the rat retina, J. Ultrastruct. Res.. 39: 413 (1972).

    Article  PubMed  CAS  Google Scholar 

  12. J. A. Sturman,and G.E.Gaul I, Taurine in the brain and liver of the developing human and monkey J. Neurochem. f 25:831 (1975),

    Google Scholar 

  13. E. L. Berson, K. C. Hayes, A. R. Rabin, S. Y. Schmidt, and G. Watson, Retinal degeneration in cats fed casein. II.Supplementation with methionine, cysteine or taurine,Invest,Ophthalmol,, 15: 52 (1976).

    PubMed  CAS  Google Scholar 

  14. K. C. Hayes, R. E.Carey,and S. Y. Schmidt, R.Tinal degeneration associated with taurine deficiency in the cat. Science. 188: 949 (1975).

    CAS  Google Scholar 

  15. K.C. Hayes, A. R. Rabin,and E. L. Berson, A. ultrastructural study of nutritionally induced and reversed retinal degeneration in catsT Am, J.Pathol, T 78: 504 (1975).

    Google Scholar 

  16. D. R. Curtis, and G. A. R. Johnston, Amino acid transmitters in the mammalian central nervous system Eraeb-PhvsioL r 69:97 (1974).,

    Google Scholar 

  17. K.Krnjevic, Chemical nature of synaptic transmission in vertebrates, Physiol Rev., 54: 418 (1974).

    Google Scholar 

  18. P. Dolara, A. Agresti, A. Giotti,and G.Pasquini, Effect of taurine on calcium kinetics of guinea pig heart, Eur, J-Pharmacol, T 24: 352 (1973).

    CAS  Google Scholar 

  19. R. Gruener, H. Bryant, D.Markovitz, R. Huxtable,and R. Bressler, Ionic actions of taurine on nerve and muscle membranesr Electrophysiological studies, in:“Taurinen”, R Huxtable and A. Bar- beau eds., Raven Press, New York (1976).

    Google Scholar 

  20. J. D. Wei ty,M. J.McBroom, A. W.Appelt, M.B.Peterson, and W.O. Read, Effect of taurine on heart and brain electrolyte imbalances, in: “Taurine”, R. Huxtable and A. Barbeau eds., Raven Press, New York (1976).

    Google Scholar 

  21. H.Pasantes-Morales, J. Klethi, P. F. Urban, and P. Mandel, The effect of electrical stimulation, light and amino acids on the efflux of 35s-taurine from the retina of domestic fowl, Exp. Brain Res,. 19: 131 (1974).

    Google Scholar 

  22. A.Lopez Colomé, D. Erlij, and H.Pasantes-Morales, Different effects of calcium-flux-blocking agents on light and potassium stimulated release of taurine from retina, Brain Res., 113: 527 (1976).

    Google Scholar 

  23. H. Pasantes-Morales, J. Klethi, P. F. Urban, and P. Mande I, The physiological role of taurine in retina:Uptake and effect on electroretinogram(ERG)T Physiol. Chem.Phvs. T 4: 339 (1972).

    CAS  Google Scholar 

  24. N. Bonaventure, N. Wioland, and P.Mandel, Antagonists of the putative inhibitory transmitter effects of taurine and GABA in the retina,BranrRe., 80: 281 (1974).

    CAS  Google Scholar 

  25. P.F.Urban, H.Dreyfus, and P.Mandel, Influence of various amino acids on the bioelectrical response to light stimulation of a superfused frog retina, Life Sci., 18: 473 (1976).

    Google Scholar 

  26. L.K.Kaczmarek, and W. R. Adey, Modification of the direct cortical response by taurine, Electroencephalogr. CI in. Neuro- physiolv 39: 292 (1975).

    Google Scholar 

  27. K.Krnjevic, and E.PuiI, Electrophysiological studies on actions of taurine, in:“Taurine”, R. Huxtable and A. Barbeau eds., Raven Press, New York (1976).

    Google Scholar 

  28. H.L.Haas, and L. Hosli, The depression of brain-stem neurons by taurine and its interaction with strychnine and bicuculline, Brain Res.. 52: 399 (1973).

    Google Scholar 

  29. V. Sonnhof, P. Grafe, J.Krumnik, M.Linder, and L.Schindler, Inhibitory post-synaptic actions of taurine, GABA and other amino acids on motoneurons of the isolated frog spinal cord, Brain Res.. 100: 327 (1975).

    Article  PubMed  CAS  Google Scholar 

  30. M.S.Starr, and M. J.Voaden, The uptake, metabol ism ans release of taurine by rat retina in vitro. Vision Res.. 12: 1261 (1972).

    Google Scholar 

  31. M. J. Neal, D. G. Peacock, and R. D. White, Kinetic analysis of amino acid uptake by the rat retina in vitro, Br, J.Pharmac. f 47: 656 (1973).

    Google Scholar 

  32. N.Lake, J.Marshall, and M. J. Voaden, Studies on the uptake of taurine by the isolated neural retina and pigment epithelium of the frog, Biochem. Soc. Trans.. 3: 524 (1975).

    Google Scholar 

  33. G. G.S.Collins, The rates of synthesis, uptake and disappearance of taurine in eight areas of the rat central nervous system. Brain Res. T 76: 447 (1974).

    Google Scholar 

  34. J. B.Lombardini, Regional and subcellular studies on taurine in the rat central nervous system, in.: “Taurine” R. Huxtable and A. Barbeau eds., Raven Press, New York (19/6).

    Google Scholar 

  35. J. G. Jacobsen, and L.H.Smith Jr, Biochemistry and physiology of taurine and taurine derivatives, Physiol. Rev., 48: 424 (1968).

    PubMed  CAS  Google Scholar 

  36. D. B. Hope, The persistence of taurine in the brains of pyridoxine-defieient rats, J.Neurochem», 1: 364 (1957).

    Article  PubMed  CAS  Google Scholar 

  37. L.EIdjarn, The conversion of cystinamine to taurine in rat,rabbit and man, J. Biol. Chem., 206: 483 (1954).

    Google Scholar 

  38. D. Caval I ini, R. Scandurra, S. Dupré, G. Federici, L. Santoro,G. Ricci, and D. Barra, Alternative pathways of taurine biosynthesis, nn: “Taurine”, R. Huxtable and A. Barbeau eds., Raven Press. New York (1976).

    Google Scholar 

  39. W. G.Martin, N.L.Sass, L. Hill, S. Tarka, and R.C. Truex, The synthesis of taurine from sulphate. IV. An alternative pathway for taurine synthesis by the rat, Proc. Soc. Exp. Biol. Med., 141: 632 (1972).

    Google Scholar 

  40. W.G.Martin, R. C. Truex, S.Tarka,W. Gorby, and L.Hill, The synthesis of taurine from sulphate.VI. Vitamin B6 deficiency and taurine synthesis in the rat, Proc.Soc. Exp. Biol.Med., 147: 835 (1974).

    Google Scholar 

  41. I.P.Lowe, and E.Roberts, Incorporation of radioactive sulphate sulfur into taurine and other substances in the chick embryo. J. Biol. Chem. 12: 477 (1955).

    Google Scholar 

  42. L.J.Machlin, and P. B.Pearson, Studies on utilization of sulphate sulfur for growth of the chicken, Proc. Soc. Exp. Biol. Med., 93: 204 (1956).

    Google Scholar 

  43. L. J. Machi in, P. B.Pearson, and C. A, Denton, The utilization of sulphate sulfur for the synthesis of taurine in the developing chick embryo. J. Biol. Chem., 212: 469 (1954).

    Google Scholar 

  44. W. G.Martin, R. C. Truex, S. Tarka, L. Hi11 and W. Gorby, The synthesis of taurine from sulphate. VHP. A constitutive enzyme in mammals, Proc. Soc. Exp. Biol.Med., 147: 563 (1974).

    Google Scholar 

  45. K.C.Hayes, A review of the biological function of taurine, Nutr.Rev., 34: 161 (1976).

    Google Scholar 

  46. R.M. Di Giorgio, G„ Tucci, and S.Macaione, Cysteine oxidase activity in rat retina during development, Life Sci., 16: 429

    Google Scholar 

  47. C. H.Misra, and J. W. Olney, Cysteine oxidase in brain. Brain Res., 97: 117 (1975).

    Google Scholar 

  48. S.Macaione, G. Tucci, G. De Luca, and R.M. Di Giorgio, Subcellular distribution of taurine and cysteine sulphinate decarboxylase activity in ox retina, J Neurochem., 27: 1411 (1976).

    Google Scholar 

  49. H.Pasantes-Morales, R.Salceda A.M.Lopez Calomp, and P.Mandel, Cysteine sulphinate aecarboxyI ase in chick and rat retina during development, J. Neurochem., 27: 11 03 (1976).

    Google Scholar 

  50. R.M.Di Giorgio, S.Macaione, and G. De Luca, S.bcellular distribution of hypotaurine oxidase activity in ox retina. Life Sc. 20: 1657 (1977).

    Google Scholar 

  51. R.M.Di Giorgio, G. De Luca, and S.Macaione, Hypotaurine oxidase activity in retinaT BulLMolec- Biol Med, T 3: 115 (1978).

    Google Scholar 

  52. S. Papa, A. G. Secchi, N. E. Lofrumento, F. D’Ermo, and E. Quagl iariel lo. Studi sul la fosfori Iazione ossidativa nei mitocon- dri di retina, Italian J. Biochem., 14: 175 (1975).

    Google Scholar 

  53. J. L.Mangan, and V. P. Whittaker, The distribution of free amino acids in subcellular fractions of guinea-pig brain, Biochem. J., 98: 128 (1966).

    Google Scholar 

  54. S.Macaione, G. Tucci, and R.M. Di Giorgio, Taurine distribution in rat tissues during development. Italian J Biochem, 24: 1 62 (1975).

    Google Scholar 

  55. K. Yamaguchi, S. Sakakibara, and I.Veda, Indution and activation of cysteine oxidase of rat liver. Biochim Biophys. Acta. 237: 502 (1971).

    CAS  Google Scholar 

  56. M.C. Guion-Rain, and F.Chatagner, Rat liver cysteine sulphinate decarboxylase rsome observations about substrate specificity, 276: 272 (1972).

    Google Scholar 

  57. A.N.Davison, Amino acid decarboxylase in rat brain and liver, Biochim Biophys. Acta. 19: 66 (1956).

    Google Scholar 

  58. E.Peck, and J. Awapara, Formation of taurine and isethionic acid in rat brain. Biochim. Biophys. Acta. 141: 499 (1967).

    Google Scholar 

  59. J. Awapara, and W. J. Wingo, On the mechanism of the taurine formation from cysteine in the rat. J. Biol. Chem.. 203: 189 (1953).

    PubMed  CAS  Google Scholar 

  60. D. Cavallini, and B.Mondovi, Sull a presenza di un nuovo metabolita nelle urine di ratto alimentato con L-cistina. Giornale di Biochimica, 1: 170 (1951).

    CAS  Google Scholar 

  61. D.Cavallini, B.Mondovi, and C. De Marco, The isolation of pure hypotaurine from the urine of rats fed cysteine. J. Biol.Chem.. 216: 577 (1955).

    Google Scholar 

  62. S.S. Oja, M.L.Karvonen, and P. Lahdesmaki, Biosynthesis of taurine and enhancement of decarboxylation of cysteine sul- phinate and glutamate by the electrical stimulation of rat brain slices, Brain Res.. 55: 173 (1973).

    Article  PubMed  CAS  Google Scholar 

  63. J.Marshall. P. A.Medford, and M. J.Voaden, Subcellular fractionation of the rabbit retina: the isolation of synaptic pedicles and inner segments of photoreceptor eel I s. Exp. Eye Res.. 19: 559 (1974).

    Google Scholar 

  64. R. L.Mathur, J. Klethi, M. Ledig, and P.Mandel, Cysteine sulphinate decarboxylase in the visual pathway of adult chicken, Life Sci. 18: 75 (1976).

    Google Scholar 

  65. H.Pasantes-Morales, R.Salceda, and A.M.Lopez Colomé, Taurine in normal retina, ¡n: “Taurine and Neurological Disorders”, A. Barbeau and R. J. Huxtable eds., Raven Press, New York (1978).

    Google Scholar 

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Author information

Authors and Affiliations

  1. Department of Biochemistry, University of Messina, Italy

    Salvatore Macaione, Rosa Maria Di Giorgio & Grazia De Luca

  2. Department of Pharmacology, University of Messina, Italy

    Giuseppe Nisticò

Authors
  1. Salvatore Macaione
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  2. Rosa Maria Di Giorgio
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  3. Grazia De Luca
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  4. Giuseppe Nisticò
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Editor information

Editors and Affiliations

  1. University of Rome, Rome, Italy

    Doriano Cavallini

  2. Institute for Basic Research in Mental Retardation, Staten Island, New York, USA

    Gerald E. Gaull

  3. University of Naples, Naples, Italy

    Vincenzo Zappia

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© 1980 Plenum Press, New York

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Macaione, S., Di Giorgio, R.M., De Luca, G., Nisticò, G. (1980). Taurine Biosynthesis in Ox Retina. In: Cavallini, D., Gaull, G.E., Zappia, V. (eds) Natural Sulfur Compounds. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-3045-5_23

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  • DOI: https://doi.org/10.1007/978-1-4613-3045-5_23

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4613-3047-9

  • Online ISBN: 978-1-4613-3045-5

  • eBook Packages: Springer Book Archive

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