Averaged Evoked Potentials and Sensory Experience

  • Stephen W. Harkins
  • Willie K. Dong


Drawing relationships between stimulus parameters, physiological response of peripheral nerves and subsequent report of sensation is possible for the skin senses in man because of the accessibility of the peripheral somatosensory system (Gybels and van Hees, 1972). Such relationships, however, are more difficult to obtain when the physiological responses of the central nervous system are considered. One approach to this problem has been to determine the stimulus-response relation of central neural activity in animals and to correlate this relation to human psychophysical responses (Mountcastle and Darian-Smith, 1968; Mountcastle, Talbot, Sakata, and Hyvärinen, 1969). A second approach has been to directly relate central neural activity to psychophysical responses in human subjects. Franzén and Offenloch (1969), for example, have demonstrated a relation between magnitude of cortical evoked potentials and perceived stimulus intensity in man. Both cortical potentials and psychophysical responses were power functions of stimulus intensity.


Stimulus Intensity Sensory Experience Clinical Neurophysiology Dental Pain Tooth Pulp 
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Copyright information

© Plenum Press, New York 1979

Authors and Affiliations

  • Stephen W. Harkins
    • 1
  • Willie K. Dong
    • 2
  1. 1.Medical CenterUniversity of Washington and Seattle Veterans Administration HospitalUSA
  2. 2.Department of Anesthesiology Medical CenterUniversity of WashingtonUSA

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