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Averaged Evoked Potentials and Sensory Experience

  • Stephen W. Harkins
  • Willie K. Dong

Abstract

Drawing relationships between stimulus parameters, physiological response of peripheral nerves and subsequent report of sensation is possible for the skin senses in man because of the accessibility of the peripheral somatosensory system (Gybels and van Hees, 1972). Such relationships, however, are more difficult to obtain when the physiological responses of the central nervous system are considered. One approach to this problem has been to determine the stimulus-response relation of central neural activity in animals and to correlate this relation to human psychophysical responses (Mountcastle and Darian-Smith, 1968; Mountcastle, Talbot, Sakata, and Hyvärinen, 1969). A second approach has been to directly relate central neural activity to psychophysical responses in human subjects. Franzén and Offenloch (1969), for example, have demonstrated a relation between magnitude of cortical evoked potentials and perceived stimulus intensity in man. Both cortical potentials and psychophysical responses were power functions of stimulus intensity.

Keywords

Stimulus Intensity Sensory Experience Clinical Neurophysiology Dental Pain Tooth Pulp 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. Beck, C., & Rosner, B. S. Magnitude scales and somatic evoked potentials to percutaneous electrical stimulation. Physiology and Behavior, 1968, 3, 947–953.CrossRefGoogle Scholar
  2. Buchwald, J. & Huang, C. Far-field acoustic response: Origins in the cat. Science, 1975, 189, 382–384.PubMedCrossRefGoogle Scholar
  3. Carmon, A., Mor, J., 6 Goldberg, J. Application of laser to psychophysiological study of pain in man. In J. J. Bonica & D. Albe-Fessard (Eds.), Advances in pain research and therapy (Vol. 1 ). New York: Raven Press, 1976a.Google Scholar
  4. Carmon, A., Mor, J., & Goldberg, J. Evoked cerebral responses to noxious thermal stimuli in humans. Experimental Brain Research, 1966, 25, 103–107.Google Scholar
  5. Chapman, C. R., Chen, A., & Bonica, J. Effects of intrasegmental electrical acupuncture on dental pain: Evaluation by threshold estimation and sensory decision theory. Pain, 1977, 3, 213–227.Google Scholar
  6. Chapman, C. R., Gehrig, J., & Wilson, M. Acupuncture compared with 33 percent nitrous oxide for dental analgesia. Anesthesiology, 1975, 42, 532–537.PubMedCrossRefGoogle Scholar
  7. Chapman, C. R. & Harkins, S. W. Cerebral evoked responses as correlates of laboratory pain. In J. J. Bonica & J. C. Liebaskind (Eds.), Advances in pain research and therapy(Vol. III). New York: Raven Press, (In Press).Google Scholar
  8. Chatrian, G. E., Canfield, R. C., Knauss, T. A., & Lettich, E. Cerebral responses to electrical tooth pulp stimulation in man. Neurology, 1975, 25, 745–757.Google Scholar
  9. Chatrian, G. E., Farrell, D. F., Canfield, R. C., & Lettich, E. Congenital insensitivity to noxious stimuli. Archives of Neurology, 1975, 32, 141–145.Google Scholar
  10. Chizppa, K. H., Choi, S. K., & Young, R. R. Short latency somato-sensory evoked potentials following median nerve stimulation in patients with neurological lesions. In J.. E. Desmedt (Ed.) Progress in Clinical Neurophysiology. Basel: Karger, 1978.Google Scholar
  11. Collins, W. F., Nulsen, F. E., & Randt, C. T. Relation of peripheral nerve fiber size and sensation in man. Archives of Neurology, 1960, 381–385.Google Scholar
  12. Cracco, R. Q. The initial positive potential of the human scalp- recorded somatosensory evoked response. Electroencephalography and Clinical Neurophysiology, 1972, 32, 623–629.PubMedCrossRefGoogle Scholar
  13. Cracco, R. Q. & Cracco, J. B. Somatosensory evoked potential in man: Far field potentials. Electroencephalography and Clinical Neurophysiology, 1976, 41, 460–466.Google Scholar
  14. Dong, W. & Harkins, S. W. Origins of somatosensory near and far-field evoked potentials. (In preparation).Google Scholar
  15. Frazen, 0 & Offenloch, K. Evoked response correlates of psycho-physical magnitude estimates for tactile stimulation in man. Experimental Brain Research, 1969, 8, 1–18.Google Scholar
  16. Green, D. M. & Swets, J. A. Signal detection theory and psycho- physics. New York: Krieger, 1974 ( Reprint of 1966 Edition).Google Scholar
  17. Gybels, J. & Van Hees, J. Unit activity from mechanoreceptors in human peripheral nerve during intensity discrimination of touch. In G. G. Somjen (Ed.), Neurophysiology studied in man. Amsterdam: Excerpta Medica, 1972.Google Scholar
  18. Halliday, A. M. Somatosensory evoked responses. In A. Redmond (Ed.), Handbook of lectroencephalography and clinical neuro-physiology. Amsterdam: Elsevier, 1975.Google Scholar
  19. Harkins, S. W., Benedetti, N., Chapman, C. R., & Colpitts, Y. Cerebral evoked potentials to noxious and non-noxious stimulation: Effects of nitrous oxide. (In Preparation).Google Scholar
  20. Harkins, S. W. & Chapman, C. R. Detection and decision factors in pain perception in young and elderly men. Pain, 1976, 2, 253–264.PubMedCrossRefGoogle Scholar
  21. Harkins, S. W. & Chapman, C. R. The perception of induced dental pain in young and elderly women. Journal of Gerontology, 1977, 32, 428–435.PubMedGoogle Scholar
  22. Harkins, S. W. & Chapman, C. R. Cerebral evoked potentials to noxious dental stimulation: Relationship to subjective pain report. Psychophysiology, 1978, 15, 248–252.PubMedCrossRefGoogle Scholar
  23. Iraqui-Madoz, V. J. & Wiederholt, W. C. Far-field somatosensory evoked potentials in the cat: Correlation with depth recording. Annals of Neurology, 1977, 569–574.Google Scholar
  24. Ivanitsky, A. J. S Strelets, V. B. Brain evoked potentials and some mechanisms of perception. Electroencephalography and Clinical Neurophysiology, 1977, 43, 397–403.PubMedCrossRefGoogle Scholar
  25. Jewett, D. L. Volume-conducted potentials in response to auditory stimuli as detected by averaging in the cat. Electroen-cephalography and Clinical Neurophysiology, 1970, 28, 609–618.CrossRefGoogle Scholar
  26. Jewett, D. L. & Williston, J. S. Auditory-evoked far fields averaged from the scalp of humans. Brain, 1971, 681–696.Google Scholar
  27. Mountcastle, V. B. & Darian-Smith, I. Neural mechanisms in somes- thesis. In V. B. Mountcastle (Ed.), Medical physiology. St. Louis: Mosby, 1968.Google Scholar
  28. Mountcastle, V. B., Talbot, W. H., Sakata, H., & Hyvarinen. J. Cortical neuronal mechanisms in flutter-vibration studied in unanesthetized monkeys. Neuronal periodicity and frequency discrimination. Journal of Neurophysiology, 1969, 32, 452– 484.Google Scholar
  29. Mumford, J. M., & Bowsher, D. Pain and protopathic sensibility. A review with particular reference to the teeth. Pain, 1976, 2, 223–244.PubMedCrossRefGoogle Scholar
  30. Rosner, B. S. & Goff, W. R. Electrical responses of the nervous system and subjective scales of intensity. In W. D. Neff (Ed.), Contributions to sensory physiology, (Vol. 2 ). New York: Academic Press, 1967.Google Scholar
  31. Schwartz, M. Averaged evoked responses and the encoding of perception. Psychophysiology, 1976, 13, 546–553.PubMedCrossRefGoogle Scholar
  32. Staddon, J. E. R. Theory of behavioral power functions. Psychological Review, 1978, 8&, 305–320.Google Scholar
  33. Stevens, S. S. Psychophysics. New York: Wiley, 1975.Google Scholar
  34. Stowell, H. Cerebral slow waves related to the perception of pain in man. Brain Research Bulletin, 1977, 2, 23–30.PubMedCrossRefGoogle Scholar
  35. Sutton, S. The specification of psychological variables in an averaged evoked potential experiment. In E. Donchin & D. B. Lindsley (Eds.), Average evoked potentials: Methods, results and evaluations. Washington, D. C.: NASA, 1969.Google Scholar
  36. Swets, J. A. The relative operating characteristic in psychology. Science, 1973, 183, 990–1000.CrossRefGoogle Scholar
  37. Uttal, W. R. Evoked brain potentials: Signs of codes? Perspectives in Biology and Medicine, 1967, 10, 627–639.PubMedGoogle Scholar
  38. Vaughan, H. G. Psychological correlates of the association cortex potentials. In A. Redmond, (Ed.), Handbook of electroencephalography and clinical neurophysiology, (Part A). Amsterdam: Elsevier Scientific Publishing Co., 1975a.Google Scholar
  39. Vaughan, H. G. Psychophysical relations of evoked responses. In A. Remond, (Ed.), Handbook of electroencephalography and clinical neurophysiology. ( Part A) Amsterdam: Elsevier Scientific Publishing Co., 1975b.Google Scholar
  40. Wiederholt, W. G., & Iragui-Madoz, V. J. Far-field somatosensory potentials in the rat. Electroencephalography and ClinicalGoogle Scholar
  41. Adair, E. R., Stevens, J. C., & Marks, L. E. Thermally induced pain, the doe scale, and the psychophysical power law. American Journal of Psychology, 1968, 81, 147–164.Google Scholar
  42. Anderson, K. V., Rosing, H. S., & Pearl. G.-S. Physiological and anatomical studies revealing an extensive transmedian innervation of feline canine teeth. In D. S. Anderson & B. Mathews (eds.), Pain in the trigeminal region. Amsterdam: Elsevier Pub. Co., 1977.Google Scholar
  43. Brookhart, H. M., Livingston, W. K., & Haugen, F.. P. Functional characteristics of afferent fibers from tooth pulp of cat. Journal of Neurophysiology, 1953, 16, 634–642.PubMedGoogle Scholar
  44. Chatrian, G. E., Canfield, R. C., Knauss, T. A., & Leftich, E. Cerebral responses to electrical tooth pulp stimulation in man. An objective correlate of acute experimental pain. Neurology, 1975, 25, 745–757.Google Scholar
  45. Goetzl, F. R., Burrill, D. Y., & Ivy, A. C. A critical analysis of algesimetric methods with suggestions for a useful procedure. Quarterly Bulletin Northwestern University Medical School, 1943, 17, 280–291.Google Scholar
  46. Hardy, J. D., Wolff, H. G., & Goodell, H. Pain sensations and reactions. Baltimore: Williams & Wilkins, Co., 1952.Google Scholar
  47. McBurney, D. H. Acupuncture, pain and signal detection theory. Science, 1974, 189, 66.Google Scholar
  48. McBurney, D. H. Signal detection theory and pain. Anesthesiology, 1976, 44, 356–358.PubMedCrossRefGoogle Scholar
  49. Stowell, H. Single-epoch somatosensory evoked potentials at vertex a time window specified for electro-ocular monitoring. Electroencephalography and Clinical Neurophysiology, 1979, 46, 220–223.PubMedCrossRefGoogle Scholar

Copyright information

© Plenum Press, New York 1979

Authors and Affiliations

  • Stephen W. Harkins
    • 1
  • Willie K. Dong
    • 2
  1. 1.Medical CenterUniversity of Washington and Seattle Veterans Administration HospitalUSA
  2. 2.Department of Anesthesiology Medical CenterUniversity of WashingtonUSA

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