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An Assay for Schizophrenia: Mass Spectrometry Determination of Two Cadaverine Metabolites

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Recent Developments in Mass Spectrometry in Biochemistry and Medicine

Abstract

Some findings indicate that cadaverine and its acylated metabolites monoacetylcadaverine and monopropionylcadaverine may be associated with schizophrenia. Monoacetylcadaverine and monopropionylcadaverine were isolated from urine of schizophrenic patients (1). It was speculated that their presence in the urine may reflect an abnormal metabolism of cadaverine concomitant with mental illness (2). We have reported recently that the blood concentrations of acylated cadaverines are significantly increased in schizophrenic patients in comparison to those in nonschizophrenic subjects (3).

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© 1979 Plenum Press, New York

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Dolezalova, H., Stepita-Klauco, M., van der Velde, C., Cassone, V. (1979). An Assay for Schizophrenia: Mass Spectrometry Determination of Two Cadaverine Metabolites. In: Frigerio, A. (eds) Recent Developments in Mass Spectrometry in Biochemistry and Medicine. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-3018-9_21

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  • DOI: https://doi.org/10.1007/978-1-4613-3018-9_21

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4613-3020-2

  • Online ISBN: 978-1-4613-3018-9

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