Abstract
Applications of mass spectrometry performed in the Merck research laboratories and which illustrate the use of techniques discussed in previous chapters are described here. The data presented were obtained by using the following instruments (Chapter 2):
-
(i)
LKB 9000S low-resolution mass spectrometer equipped with a gas chromatographic inlet and a Systems Industries 150 data acquisition system,
-
(ii)
LKB 9000 instrument with Varian 620i data system, and
-
(iii)
AEI MS902 high-resolution mass spectrometer equipped with a gas chromatographic inlet and a modified AEI DS30 data system.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
Reference
G. Horváth, inProgress in Drug Research (E. Juker, ed.), Vol. 18, Birkhaüser Verlag, Basel, 1974, pp. 399–473.
B. J. Millard, inAdvances in Drug Research (N. J. Harper and A. B. Simmonds, eds.), Vol. 6, Academic Press, New York, 1971, pp. 157–231.
C. G. Hammer, B. Holmstedt, J. E. Lindgren, and R. Tham, inAdvances in Pharmacology and Chemotherapy (S. Garattini, A. Goldin, F. Hawkins, and I. J. Kapin, eds.), Vol. 7, Acadmeic Press, New York, 1969, pp. 53–89.
E. Costa and B. Holmstedt (eds.),Advances in Biochemical Psychopharmacology, Vol. 7, Raven Press, New York, 1973.
D. J. Jenden and A. K. Cho,Ann. Rev. Pharmacol. 13, 371–390 (1973).
S. Ahuja, Derivatization in gas chromatography,J. Pharm. Sci. 65, 163–182 (1976).
W. J. A. VandenHeuvel and A. G. Zacchei, Gas-liquid chromatography in drug analysis, inAdvances in Chromatography (J. C. Giddings, ed.), Vol. 14, Marcel Dekker, Inc., New York, 1976, pp. 199–263.
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1979 Plenum Press, New York
About this chapter
Cite this chapter
Zacchei, A.G., VandenHeuvel, W.J.A. (1979). Applications of Mass Spectrometry in the Pharmaceutical Industry. In: Middleditch, B.S. (eds) Practical Mass Spectrometry. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-2982-4_11
Download citation
DOI: https://doi.org/10.1007/978-1-4613-2982-4_11
Publisher Name: Springer, Boston, MA
Print ISBN: 978-1-4613-2984-8
Online ISBN: 978-1-4613-2982-4
eBook Packages: Springer Book Archive