Abstract
The purpose of our applying acoustic tomographic methods in the breast is directed toward the early detection of carcinoma of the breast. Our rationale is based on the principle that early detection of cancer is not only dependent upon the spatial resolution of the physical method of detection but also depends upon sensitivity for detecting changes in basic properties of tissue which can be logically related to the normal and abnormal histologic elements and spatial organization of the organ under investigation. For the breast, detection of such changes demands methods which are capable of delineating the basic elements of the normal breast such as fat, inter- and intralobar connective tissue, ducts and acinar tissue as well as the localization of common lesions of the breast such as fibrocystic disease, cysts, fibroadenomas, medullary carcinoma, and scirrhous carcinoma. Development of such capabilities of histologic and spatial tissue differentiation should allow one not only to find an established advanced lesion, but also to detect early changes in the morphology of the normal breast by detecting focal changes in the acoustic properties of normal tissue constituents which may imply the presence or the potential of development of a neoplasm.
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© 1980 Plenum Press, New York
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Greenleaf, J.F., Kenue, S.K., Rajagopalan, B., Bahn, R.C., Johnson, S.A. (1980). Breast Imaging by Ultrasonic Computer-Assisted Tomography. In: Metherell, A.F. (eds) Acoustical Imaging. Acoustical Imaging, vol 8. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-2943-5_37
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