Dietary Control of Central Cholinergic Activity

  • R. J. Wurtman
  • J. H. Growdon

Abstract

This chapter describes the relationship between choline — administered as choline chloride or as phosphatidylcholine (lecithin), by injection or via the diet — and tissue acetylcholine (ACh) levels, and shows that choline administration, by raising blood and brain choline levels, can be a major determinant of the rate of ACh synthesis and, probably, of the amount of the neurotransmitter released when cholinergic neurons are depolarized.

Keywords

Dopamine Tyrosine Serotonin Histamine Epinephrine 

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Copyright information

© Plenum Press, New York 1979

Authors and Affiliations

  • R. J. Wurtman
    • 1
  • J. H. Growdon
    • 1
    • 2
  1. 1.Laboratory of Neuroendocrine Regulation, Department of Nutrition and Food ScienceMassachusetts Institute of TechnologyCambridgeUSA
  2. 2.Department of NeurologyTufts University Medical SchoolBostonUSA

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