Anterior-pituitary function before and after transsphenoidal microsurgery for pituitary tumors
The introduction of transsphenoidal microsurgery represents a major improvement in the surgical management of functioning and non-functioning pituitary tumors. A distinct advantage of this technique is the ability to achieve selective tumor removal with preservation of normal pituitary tissue, especially in patients with small adenomas. Numerous reports in the literature have underscored the success of transsphenoidal surgery in correcting the hypersecretion of prolactin , growth hormone , and ACTH  due to a functioning pituitary adenoma. As it might be expected, the success of the surgery has been found to be inversely related to the size of the tumor, with the best results obtained in patients with microadenomas (i.e. <10 mm in diameter).
KeywordsAdenoma Cortisol Prolactin Hypoglycemia Hypothyroidism
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