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Prolymphocytic Leukemia of B- and T-Cell Types

Morphological Differences by Light and Electron Microscopy
  • Daniel Catovsky
  • Estela Matutes
  • Alistair D. Crockard
  • Maureen O’Brien
  • Christine Costello
Part of the Developments in Oncology Series book series (DION, volume 14)

Abstract

Prolymphocytic leukemia (PLL) is a distinct variant of chronic lymphocytic leukemia (CLL) [1, 2]. Although PLL may be suspected in patients with massive splenomegaly and lymphocyte counts over 100 × 109/1, the diagnosis can be made only by identifying the prolymphocyte as the predominant cell in well-prepared peripheral blood films. The typical morphological features of the prolymphocyte—namely, larger size than a normal blood lymphocyte (or CLL) slightly more cytoplasm, and a prominent nucleolus—are best appreciated at ultrastructural level [1, 3–7].

Keywords

Chronic Lymphocytic Leukemia Cytoplasmic Granule Large Granule Massive Splenomegaly Fischer Exact Test 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Martinus Nijhoff Publishing, Boston/The Hague/Dordrecht/Lancaster 1984

Authors and Affiliations

  • Daniel Catovsky
  • Estela Matutes
  • Alistair D. Crockard
  • Maureen O’Brien
  • Christine Costello

There are no affiliations available

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