Tactile Sensation Related to Activity in Primary Afferents with Special Reference to Detection Problems

  • Å B. Vallbo
Part of the Wenner-Gren Center International Symposium Series book series (EMISS, volume 12)


An ultimate goal in the study of sensory mechanisms is to arrive at an understanding of how the brain produces useful sensations on the basis of afferent information from sense organs. An attractive approach which bridges the gap between physiology and psychology is to analyse the correlations between neuronal events and psychophysical test data. This field was first explored, with the resolution of single unit discharges, by Mountcastle and co-workers about 20 year ago when the now classical papers on correlations between psychophysical data extracted from human subjects were related to activity in first order afferents studied in monkeys (Werner & Mountcastle, 1965, 1968; Talbot et al. 1968; Mountcastle et al. 1969). One conclusion drawn from their studies on vibrotactile sensation was “that the detection capacity of the alert and attending subject appears to be set by the peripheral neuronal threshold; it is not elevated by any higher central threshold” (Mountcastle, 1975).


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  1. Chambers, M.R., Andres, K.H., von Duering, M., Iggo, A. (1972). The structure and function of the slowly adapting type II mechanoreceptors in hairy skin. Q. JL exp. Physiol., 57, 417–445Google Scholar
  2. Green, D.M., Swets, J.A. (1966). Signal detection theory and psychophysics. Wiley, New YorkGoogle Scholar
  3. Hecht, S., SchLaer, S., Pirenne, M.H. (1942). Energy, quanta and vision. J. Gen. Physiol., 25, 819–840PubMedCentralPubMedCrossRefGoogle Scholar
  4. Hensel, H., Boman, K.A., (1960). Afferent impulses in cutaneous nerves in human subjects. J. Neurophysiol., 23, 564–578PubMedGoogle Scholar
  5. Iggo, A. (1974). Cutaneous receptors. In The peripheral nervous system. (ed. J.I. Hubbard) Plenum Press, New York, pp. 347–404CrossRefGoogle Scholar
  6. Iggo, A., Muir, A.R. (1969). The structure and function of a slowly adapting touch corpuscle in hairy skin. J. Physiol., Lond., 200, 763–796PubMedCentralPubMedGoogle Scholar
  7. Johansson, R.S. (1978). Tactile sensibility in the human hand: receptive field characteristics of mechanoreceptive units in the glabrous skin area. J. Physiol., Lond., 281, 101–123PubMedCentralPubMedGoogle Scholar
  8. Johansson, R.S., Vallbo. Å.B. (1976). Skin mechanoreceptors in the human hand: An inference of some population properties. In Sensory functions of the Skin in Primates, with special reference to Man. (ed. Y. Zotterman). Pergamon Press, Oxford, pp. 71–184Google Scholar
  9. Johansson, R.S., Vallbo, Å.B. (1979a). Tactile sensibility in the human hand: relative and absolute densities of four types of mechanoreceptive units in glabrous skin. J. Physiol., Lond., 286, 283–300PubMedCentralPubMedGoogle Scholar
  10. Johansson, R.S., Vallbo, Å.B. (1979b). Detection of tactile stimuli. Thresholds of afferent units related to psychophysical thresholds in the human hand. J. Physiol., Lond., 197, 405–422Google Scholar
  11. Johansson, R.S., Vallbo, Å.B. (1980). Spatial properties of the population of mechanoreceptive units in the glabrous skin of the human hand. Brain Res., 184, 353–366PubMedCrossRefGoogle Scholar
  12. Johansson, R.S., VaLLbo, Å.B. and Westling, G. (1980). Threshold of mechanosensitive afferents in the human hand as measured with von Frey hairs. Brain Res., 184, 343–351PubMedCrossRefGoogle Scholar
  13. Knibestöl, M., (1973). Stimulus-response functions of rapidly adapting mechanoreceptors in the human glabrous skin area. J. Physiol., Lond., 232, 427–452PubMedCentralPubMedGoogle Scholar
  14. Knibestöl, M. (1975). Stimulus-response functions of slowly adapting mechanoreceptors in the human gLabrous skin area. J. Physiol., Lond., 245, 63–80PubMedCentralPubMedGoogle Scholar
  15. KnibestöL, M., Vallbo, Å.B. (1970). Single unit analysis of mechanoreceptor activity from the human glabrous skin. Acta physiol. sand., 80, 178–195CrossRefGoogle Scholar
  16. Konietzny, F., Perl. E.R., Trevino, D., Light, A., Hensel. H. (1981). Sensory experiences in man evoked by intraneural electrical stimulation of intact cutaneous afferent fibres. Exp. Brain Res., 42, 219–222PubMedCrossRefGoogle Scholar
  17. Mountcastle, V.B., (1975). The view from within: Pathways to the study of perception. The Johns Hopkins Medical Journal, 136, 109–131PubMedGoogle Scholar
  18. Mountcastle. V.B., Talbot, W.H., Sakata, H., Hyvärinen, J. (1969). Cortical neuronal mechanisms in flutter-vibration studied in unanesthetized monkeys neuronal periodicity and frequency discrimination. J. Neurophysiol., 32, 452–484PubMedGoogle Scholar
  19. Schady, W., (1983). Projections of sensory fibres in human median nerve. Acta Univ. Upsaliensis, Abstr. Uppsala DissGoogle Scholar
  20. Swets, J.A., (1964). (ed.) Signal detection and recognition by human observers: Contemporary readings. Wiley, New YorkGoogle Scholar
  21. Talbot, W.H., Darian-Smith, I., Kornhuber, H.H., Mountcastle, V.B. (1968). The sense of flutter-vibration: Comparison of the human capacity with response patterns of mechanoreceptive afferents from the monkey hand. J. Neurophysiol., 31, 301–334PubMedGoogle Scholar
  22. Torebjörk, H.E., Ochoa, J.L. (1980). Specific sensations evoked by activity in single identified sensory units in man. Acta Physiol. Scand. 110, 445–447PubMedCrossRefGoogle Scholar
  23. Vallbo, Å.B. (1976). Prediction of propagation block on the basis of impulse shape in single unit recordings from human nerves. Acta physiol. Scand., 97, 66 - 74PubMedCrossRefGoogle Scholar
  24. Vallbo,, Å.B. (1981). Sensations evoked from the glabrous skin of the human hand by electrical stimulatin of unitary mechanosensitive afferents. Brain Res., 215, 359–363PubMedCrossRefGoogle Scholar
  25. Vallbo, Å.B., Hagbarth, K.-E. (1967). Impulses recorded with microeLectrodes in human muscle nerves during stimulation of mechanoreceptors and voluntary contractions. Electroen. Neurophysiol., 23, 392Google Scholar
  26. Vallbo, Å.B., Hagbarth, K.-E. (1968). Activity from skin mechanoreceptors recorded percutaneously in awake human subjects. Exptl. Neural., 21, 270–289CrossRefGoogle Scholar
  27. Vallbo, Å.B., Johansson, R.S. (1976). Skin mechanoreceptors in the human hand: Neural and psychophysical thresholds. In Sensory Functions of the Skin in Primates, with special reference to Man. (ed. Y. Zotterman). Pergamon Press, Oxford, pp. 185–199Google Scholar
  28. Vallbo, Å.B., Johansson, R.S. (1978). The tactile sensory innervation of the glabrous skin of the human hand. In Active Touch: The Mechanisms of Recognition of Objects by Manipulation. A Multi-disciplinary approach. (ed. G. Gordon) Pergamon Press, Oxford, pp. 29–54Google Scholar
  29. Werner, G., MountcastLe. (1965). Neural activity in mechanoreceptive cutaneous afferents: Stimulus-response relations, Weber functions, and information transmission. J. Neurophysiol., 28, 359–397PubMedGoogle Scholar
  30. Werner, G., Mountcastle, V.B., (1968). Quantitative relations between mechanical stimuli to the skin and neural responses evoked by them. In The skin senses (ed. D.R. Kenshalo) C.C. Thomas, Springfield, pp. 112–137Google Scholar
  31. Westling, G., Johansson, R.S., Vallbo, Å.B. (1976). A method for mechanical stimulation of skin receptors. In Sensory functions of the Skin in Primates, with special reference to Man. (ed. Y. Zotterman) Pergamon Press, Oxford, pp. 151–153Google Scholar

Copyright information

© The Wenner-Gren Center 1984

Authors and Affiliations

  • Å B. Vallbo
    • 1
  1. 1.Nobel Institute of NeurophysiologyKarolinska InstitutetStockholmSweden

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