Abstract
The purpose of this communication is to briefly review a series of studies, initiated with Sid Riegelman and carried on by a second generation of graduate students, on mechanisms involved in the intestinal conjugation of drugs.
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References
W.H. Barr and S. Riegelman, Intestinal drug absorption and metabolism I. Comparison of methods and models to study physiological variables ofin vitro andin vivo intestinal absorption, J. Pharm. Sci. 59: 154–163 (1970).
W.H. Barr and S. Riegelman, Intestinal drug absorption and metabolism II. Kinetic aspects of intestinal glucuronide conjugation, J. Pharm. Sci. 59: 164–168 (1970).
W.H. Barr, T. Aceto, M. Chung and M. Shukur, Dose-dependent drug metabolism during the absorptive phase, Rev. Can. Biol. 32: 21–42 (1973).
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© 1984 Plenum Press, New York
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Barr, W.H., Chung, M., Shukur, M. (1984). Intestinal Drug Metabolism — Presystemic and Systemic Mechanisms and Implications. In: Benet, L.Z., Levy, G., Ferraiolo, B.L. (eds) Pharmacokinetics. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-2799-8_35
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DOI: https://doi.org/10.1007/978-1-4613-2799-8_35
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