Molecular Mechanisms of Mutagenesis and Carcinogenesis

  • M. Kirsch-Volders
  • M. Radman
  • P. Jeggo
  • L. Verschaeve


A given mutagen interacting with the cell may induce different types of genetic lesions, ranging from a single-base modification, which might completely be restored in its initial form, to a chromatid break or to the loss of a chromosome.


Chromosomal Rearrangement Sister Chromatid Chromosome Aberration Metaphase Chromosome Sister Chromatid Exchange 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Plenum Press, New York 1984

Authors and Affiliations

  • M. Kirsch-Volders
    • 1
  • M. Radman
    • 2
    • 3
  • P. Jeggo
    • 4
    • 5
  • L. Verschaeve
    • 1
  1. 1.Laboratorium voor AntropogenetikaV.U.B.BrusselsBelgium
  2. 2.Départment de BiologieU.L.B.OrseyFrance
  3. 3.Laboratoire de GénétiqueUniversité Paris Sud, Faculté ScienceOrseyFrance
  4. 4.Département de Biologie MoléculaireU.L.B.Mill Hill, LondonEngland
  5. 5.National Institutes of Medical Research, Department of GeneticsM.R.C.Mill Hill, LondonEngland

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