Abstract
The aminoglycoside antibiotics are widely used in the pediatric age population for the treatment of serious gram negative infections. The incidence of nephrotoxicity in patients receiving aminoglycosides varies according to the criteria defining nephrotoxicity, the aminoglycoside used, and the presence or absence of risk factors. One proposed risk factor is sodium depletion. Although clinical information is largely anecdotal, substantial experimental data support the influence of sodium balance on aminoglycoside nephrotoxicity.
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© 1986 Martinus Nijhoff Publishing, Boston
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Adelman, R.D. (1986). Aminoglycoside Nephrotoxicity — Clinical and Experimental Observations. In: Strauss, J. (eds) Homeostasis, Nephrotoxicity, and Renal Anomalies in the Newborn. Developments in Nephrology, vol 11. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-2637-3_6
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DOI: https://doi.org/10.1007/978-1-4613-2637-3_6
Publisher Name: Springer, Boston, MA
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