Recombinant DNA Technology for the Production of Plasma Proteins
During the past few years we have seen an unparalleled interest and growth in applied biology. The rapid progress in this area has been largely driven by laboratory advances in monoclonal antibody and recombinant DNA (r-DNA) techniques. Most of the early efforts to apply r-DNA technology to commercial product development were directed toward the production of small peptide hormones such as interferon, insulin and growth hormone. The only r-DNA produced therapeutic agent currently on the market is the human insulin preparation sold by Eli Lilly and Company. However, many observers believe that a human growth hormone preparation produced by Genentech could be available in 1985 and a number of other therapeutic agents such as tissue plasminogen activator are presently undergoing clinical trials.
KeywordsFermentation Hepatitis Albumin Carbohydrate Carboxylate
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