Abstract
Coronary artery disease remains the most serious public health problem in the Western world. In the United States alone, each year there are 1,250,000 myocardial infarctions (MI) and 650,000 patients die as a result of their acute MI. The loss of viable myocardium in those patients who survive acute infarction also leads to major morbidity from heart failure and cardiac arrhythmias. Coronary care units, which were developed in the late 1960s and early 1970s, have been able to provide close observation and electrocardiographic monitoring of patients with acute MI and have reduced the number of deaths due to arrhythmias and conduction disturbances. In recent years, however, in-hospital deaths from acute infarction have not changed significantly [1] despite the many advances in cardiovascular therapy and technology. Most in-hospital deaths related to acute MI now are due to pump failure.
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References
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Stone, P.H., Rude, R.E., Muller, J.E., Braunwald, E. (1985). Current Status of Interventions Designed to Limit Infarct Size. In: Levine, H.J., Gaasch, W.H. (eds) The Ventricle. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-2599-4_15
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